130 results
Systematic gathering of biomaterial and phenotypic data of IBD patients during clinical care provides assessment of molecular markers in the DNA, the transcriptome and proteome. The markers can be associated with the different disease phenotypes…
Main objectivesCohort study:To investigate the prognostic implications of skin sodium accumulation for CKD patients.Sodium excretion intervention study:To study the effect of increased renal sodium excretion, with and without …
To compare the efficacy of PPS above the ampulla to standard EBD in patients with MHBO who are ineligible for surgical resection.
This study evaluates the efficacy and applicability of schema therapy for anorexia nervosa.
The primary objective of this study is to determine the nutritional intake, nutritional status, and physical activity level at various moments post-lower limb amputation (i.e., during hospital admission for amputation, at 5 weeks post-amputation, at…
To study the human adult cochlea, in specific it's RNA and protein expression patterns and morphology.
Primary Objective: To prospectively identify, in routine daily practice, the impact of radiotherapy to extremities, with regard to the incidence of (severe) ALT or AST elevations in STS patients (all grades, no systemic therapy). Secondary Objective…
Primary objectives: 1. To assess the difference in bioprosthetic leaflet 18F-NaF PET activity, as an early marker of transcatheter valve degeneration, between patients with vs. without SCLT at five years after TAVI.2. To assess the difference in…
The primary objective of this clinical trial is to further evaluate the clinical efficacy of the Corvia Atrial Shunt in symptomatic heart failure patients with a left ventricular ejection fraction (LVEF) >= 40%, and elevated left sided…
The proposed pilot study will examine whether radiation-based CTA could be replaced with MRI in three phases of AAA management.
The main objective of this study is to evaluate the clinical effects of SCS on the number and intensity of VSA attacks. Secondary objective is to objectivate the effects of SCS on coronary spasms during the provocative acetylcholine test, and assess…
Demonstrating or ruling out metastasis of prostate cancer is necessary to draw up a good treatment plan and helps to estimate the course of the disease. The aim of this study is to find out whether use of the radioactive contrast agent 18F-FAPI-74…
In the present study we aim to investigate the effectiveness of short-term schema group therapy (protocol of de Jager and Burger) on (1) persistent anxiety and depressive symptoms, and (2) dysfunctional schemas, experiential avoidance and the mode…
Primary Safety Objective: • To evaluate initial safety of UCon for treatment of OAB symptoms in a home setting.Secondary Safety Objective• To demonstrate that subjects using UCon do not experience an unacceptable amount of device- or procedure…
Main Objectives: 1) Are patients with ASA III score undergoing primary or revision arthroplasty of the knee or hip, able to safely participate in a home-based preoperative High Intensity Interval Training (HIIT) program? 2) Does average daily…
Our objective is to assess the association between transcutaneous diaphragm electromyography (dEMG) and diaphragm ultrasound (dUS) in the PICU population.
Primary Objective: • To contrast Coherent Mapping quality (electrograms per map) and noise assessment using Octaray (with TRUEREF technology) versus Pentaray catheter for left and right atrium.Secondary Objective(s): • To contrast the Coherent…
The clinical result of the CFP prosthesis is equal to or better than the clinical results of the SPII prosthesis in patients with osteoarthritis above the age of 70.Secondary purpose:Is there a difference between the scores of the SPII and CFP total…
To identify molecular biomarker profiles that are associated with cervical tumorigenesis, and that can be used for development of an algorithm for detection of low grade CIN1, CIN2, CIN3 and cervical cancer. The algorithm should provide advice for…
This study aims to determine the effect of nocturnal versus daytime cyclic infusion of parenteral nutrition in adult chronic intestinal failure patients on bone turnover, glucose metabolism, nitrogen balance, sleep and wake rhythm and clock genes…