389 results
Primary objectivesFor part A of the study: -To determine the feasibility of Clofarabine when given at three possible dose levels together with standard induction cycles I and II in patients with AML/ RAEB with IPSS>=1.5 in a prospective…
To improve the response rate to treatment of severe acute GVHD (grade II-IV with gut involvement ) by adding infusion of Mesenchymal Stroma Cells to standard high dose prednisolone.
Currently, no robust clinical data are available comparing interventional ablation strategies in the setting of persistent AF with enlarged Atrium > 4 cm and longstanding persistent AF, which reflects a difficult to treat patient-subgroup.…
The objective of this Phase 3 study is to investigate the safety and efficacy of benralizumab as a treatment for patients with eosinophilic gastritis and/or gastro-enteritis.
The present study has several aims. The first aim is to adapt and validate a trauma screener suitable for people with MID-BIF (Study #1), with the hypothesis that*the adapted screener would be a valid screening instrument (AUC of at least 0.8) for…
To compare the efficacy of PPS above the ampulla to standard EBD in patients with MHBO who are ineligible for surgical resection.
This study evaluates the efficacy and applicability of schema therapy for anorexia nervosa.
The primary objective of this clinical trial is to further evaluate the clinical efficacy of the Corvia Atrial Shunt in symptomatic heart failure patients with a left ventricular ejection fraction (LVEF) >= 40%, and elevated left sided…
The proposed pilot study will examine whether radiation-based CTA could be replaced with MRI in three phases of AAA management.
The main objective of this study is to evaluate the clinical effects of SCS on the number and intensity of VSA attacks. Secondary objective is to objectivate the effects of SCS on coronary spasms during the provocative acetylcholine test, and assess…
Demonstrating or ruling out metastasis of prostate cancer is necessary to draw up a good treatment plan and helps to estimate the course of the disease. The aim of this study is to find out whether use of the radioactive contrast agent 18F-FAPI-74…
In the present study we aim to investigate the effectiveness of short-term schema group therapy (protocol of de Jager and Burger) on (1) persistent anxiety and depressive symptoms, and (2) dysfunctional schemas, experiential avoidance and the mode…
Primary Safety Objective: • To evaluate initial safety of UCon for treatment of OAB symptoms in a home setting.Secondary Safety Objective• To demonstrate that subjects using UCon do not experience an unacceptable amount of device- or procedure…
Main Objectives: 1) Are patients with ASA III score undergoing primary or revision arthroplasty of the knee or hip, able to safely participate in a home-based preoperative High Intensity Interval Training (HIIT) program? 2) Does average daily…
Our objective is to assess the association between transcutaneous diaphragm electromyography (dEMG) and diaphragm ultrasound (dUS) in the PICU population.
Primary Objective: • To contrast Coherent Mapping quality (electrograms per map) and noise assessment using Octaray (with TRUEREF technology) versus Pentaray catheter for left and right atrium.Secondary Objective(s): • To contrast the Coherent…
The primary objective of the proposed study is to examine the feasibility and acceptability of VR-delivered exposure sessions in a therapy protocol for PTSD. The secondary objective is to test how effective the intervention is in reducing symptoms…
At the moment it is unknown which radiomics features are robust against variations in image characteristics. The objective of this study is to check the robustness of radiomics features, and to investigate wheter specific pre- and postprocessing…
The primary objective of this study is to estimate the efficacy of SABR for primary RCC.
The study purpose is to evaluate the acute and long term clinical performance and safety of the Evolut* PRO System used in routine hospital setting for the treatment of symptomatic native aortic valve stenosis or a stenosed, insufficient, or…