165 results
Examine the impact of 7-day daily ischemic preconditioning on brachial artery endothelial function (measured as FMD%) in the dominant arm (i.e. local effect: primary objective) and contra-lateral arm (i.e. remote effect: secondary objective) in…
The purpose of this study is to determine the need for thromboprofylaxis in patients being treated in a below-knee plaster cast after trauma of a lower extremity and if there is, to assess if both of the two tested prophylactic treatments are suited…
Is, when EE is kept constant, replacing sitting time by NEA more effective than exercise in improving glucose control in people with DM2?
1 Assessment whether using a nerve-sparing exposure of the aortoiliac tract during vascular reconstruction will lead to a neurophysiologically intact sympathetic pathway to the intra-pelvic organs and thus to an intact postoperative function.2…
To study the effects of flaxseed oil, rich in ALA on 24h-ambulatory mean arterial pressure (MAP) in men and women with high-normal blood pressure and mild hypertension compared to high oleic sunflower oil, poor in ALA.
The main aim of this implementation research is to systematically screen all RA patients of Reade rheumatology and revalidation centre in Amsterdam for their cardiovascular risk profile and if necessary to treat them for cardiovascular risk factors…
The purpose of this study is to answer the following question: Leads a primary coagulation corrected with a single dose of fibrinogen concentrate after ascending aorta-arc reconstruction to a decrease in the number of allogenic blood transfusions,…
To compare ticagrelor with clopidogrel treatment on the risk of cardiovascular death, myocardial infarction and ischaemic stroke in patients with established peripheral artery disease.
To compare the blood pressure lowering effect of thiazides against calcium channel blockers in CNI-induced hypertension.
The incidence of wound complications in endovascular aneurysm repair (EVAR). VAS scores will be obtained to objectify the advances of a percutaneous approach. Cultures and wound biopsies will be obtained from every patient. Also cost-effectiveness…
1. The primary efficacy objective is to evaluate whether rivaroxaban, in doses of 10 mg or 20 mg, is superior to ASA 100 mg in the prevention of the primary efficacy outcome (i.e. fatal or non-fatal symptomatic recurrent venous thromboembolism).2.…
OBJECTIVESThe objective is to quantify the cost-effectiveness and efficacy of formally applying the guideline evaluating the risk-benefit ratio of the duration of anticoagulant therapy (VKA treatment) by a previously developed VTE recurrence…
The FLAVO-II study will be conducted as a three-armed, randomized, cross-over intervention trial aimed at comparing the effects of chocolate and pure epicatechin on vascular function.
- to evaluate (cost-) effectiveness of a personalized health intervention among workers of 40 years and older with high physical work demands to contribute to a reduction in CVD and sustainable employability.
Comparative effectiveness research to determine cost-effectiveness of an existing healthcare policy, i.e. treatment with low molecular weight heparin (LMWH) after knee arthroscopy and lower leg plaster cast immobilization following surgical or…
PrimaryImproved woundhealing in 30 days in patients with an open revascularisation of the lower extremities after treatment with 4 dosages of 2 grams ascorbic acid on 4 consecutive days. (First dosage 1 hour preoperative)SecondaryWith preoperative…
Currently, no established risk factor profile for developing arterial cardiovascular events after an acute unprovoked PE exists and is carried out in general practice. The aim of our project is to prospectively study the relation between presence…
Our main objective is to determine the effect of HO-1 induction by heme arginate infusion on insulin resistance and endothelial dysfunction related to MetS. Secondary objectives are to determine the effect on adipose tissue, adiponectin plasma level…
The primary objectives are formulated to investigate the effect of chocolate flavanols on vascular function, inflammation, oxidative stress and markers of endothelial function. The effects of both acute consumption and prolonged consumption will be…
1. To investigate the presence of risk factors for CVD (i.e. overweight/ obesity, hypertension, diabetes and dyslipidemia,) among the Ghanaian population in Amsterdam.a) To investigate levels of detection, treatment and control of hypertension among…