469 results
The main objective of this study is to determine the role of glycaemic control in diabetes mellitus in the occurrence of acetylsalicylic acid resistance, the secondary objective is to determine the effect of increased dosing on acetylsalicylic acid…
Determine effect of asprin and simvastatin on platelet and monocyte gene expression in vivo.
In this study we will test the study hypothesis whether there is differential gene expression between patients with a history of premature MI and healthy controls when testing RNA obtained from highly purified platelets and monocytes.
1. The primary aim of REAL CAD is to determine regional differences of leukocyte activation in different vascular beds in vivo.2. The secondary aim is to investigate differences in leukocyte activation between diabetic and CAD subjects and…
Aim of this study is to quantify the relationship between the extent of aortic atherosclerotic disease and neurocognitive dysfunction after cardiac surgery with the use of cardiopulmonary bypass.
The aim of the proposed study will determine new duplex ultrasound velocity (DUS) criteria for reference/normal values and in-stent re-stenosis after aorto-iliac stenting.
Objective: to provide an answer to the following question: in patients with AD, does treatment with a ChEI improve cerebral autoregulation?
1. Is EC dysfunction, measured by PWA, present RA patients?2. Is EC dysfunction in RA related to EC activation markers (CRP, thrombomodulin, sVCAM, vWF), AGEs, and the presence of atherosclerosis?3. Is EC dysfunction related to traditional…
To evaluate the correlation between the findings from the explained non invasive vascular tools (CIMT, PWV, FMD and OPS imaging) with prevalent CVD in diabetic individuals.To evaluate the potential of non invasive vascular tools for identification…
Evaluation whether there is 99mTc-IL2 uptake in vulnerable carotid plaques of patients on long-term treatment with statins.
The aim of this clinical study is to investigate whether the non-anaesthetic noble gas helium induces EPC and LPC of human endothelium in vivo.
To determine the accuracy of Vasovist® enhanced MRA of the leg with regard to quantitative grading of stenosis (<50%, >=50%) compared to digital subtraction angiography (DSA, standard of reference (SOR))
The objective of this study is to predict which patients will develop MES after carotid endarterectomy, using different coagulation parameters and platelet function tests, so in the future these patients will be indentified early. Identification of…
This study is designed to investigate the limiting effect on infarct size of high dose intravenous adenosine during primary angioplasty
Are overweight or obese patients protected against atherosclerosis when suffering from haemophilia A? Is this association influenced by the severity of haemophilia? When the coagulation activity increases due to obesity (and inflammation), will this…
The main objectives are :Cross-sectional:1. To investigate the extent of atherosclerotic disease of the carotid artery defined as: (a) the intima-media thickness (IMT) (b) the elasticity (c) the degree of stenosis2. To define the degree of…
In this pilotstudy we will investigate if it is feasable to measure volume increase in a operated leg by means of a CT scan
To test the hypothesis in patients with either acute large middle cerebral artery territory or lacunar stroke that cerebral oxygenation is related to cerebral perfusion and becomes dependant on blood pressure at brain level if dynamic…
To organize one pool of control subjects for IMT studies.
To test the hypothesis whether the Intima Media Thickness differs between FH carriers without apparent dyslipidemia and the group of FH carriers with apparent dyslipidemia and a control group consisting of persons tested by the StOEH who did not…