469 results
Objective is to determine the stump volume change in lower limb amputees, in the post operative period. Especially interesting is to know when the stump volume stabilizes, and doesn*t decrease anymore, and if there are any fluctuations in volume.
The aim of the study is to investigate the changes in peritoneal endothelial glycocalyx in end-stage renal disease (ESRD), with the duration of peritoneal dialysis, and relate these changes to alterations in peritoneal transport and morphology.…
The overall objective of this study is to assess to what extend different cognitive domains are affected by a recent TNA and which mechanism is responsible for this cognitive decline. We wanted to know whether the kind of TNA (focal, non-focal,…
To evaluate the cost-effectiveness, from the perspectives of the health care system and of society at large, of supervised exercise compared to endovascular revascularization plus supervised exercise as first-line treatment of IC.
To setup and validate an accessible, non-invasive method to enable earlier and more precise classification of patients with an elevated or high blood pressure.
Explore 4 week post-treatment effect of seven day administration of dipyridamole on nucleoside transport inhibition.
Primary goal:To investigate whether specific plaque characteristics are associated with ischemic lesions, especially (clinically silent) cerebral micro-infarcts, we will perform preoperative high resolution 3 and 7 Tesla MR plaque imaging in…
To determine whether different circadian rhythms exist between patients with type 2 diabetes and controls in glucose responses, and whether this difference is best detected by either continuous glucose measurement or venous blood sampling. To…
2.1 Primary ObjectiveTo determine the effect of endothelial dependent and independent vasodilators on endothelial shear stress in humans. 2.2 Secondary ObjectiveTo determine the association between endothelial shear stress and endothelial function…
Given that previous studies demonstrated the feasibility of the required MRI techniques, we propose to studythe macro- and microvascular adaptations in PAOD patients undergoing supervised exercise therapy. It isexpected to provide valuable insights…
The PAPPA-trial was the first prospective clinical study the feasibility and safety of a DEB only strategy in PPCI for STEMI. One-year angiographic follow-up is warranted to evaluate long-term patency of the target lesion. So far there has not been…
Primary objective: - To assess the prevalence and severity of coronary artery disease in asymptomatic older (> 45 years) men who undergo exercise testing as part of a sports medical evaluation, with minimally invasive cardiac multidetector…
To predict the risk of particular coronary plaques to cause myocardial infarction
Primary Objective: The primary goal of this study is to obtain BM and PB from healthy controls without overt cardiovascular diseases (ie patients that undergo orthopaedic or vascular surgery [atherosclerotic disease excluded]) in order to compare…
1) Determine differences in EPC and SMPC availability in the peripheral blood of T2DM patients with or without coronary artery disease (CAD) or peripheral artery disease (PAD) as well as in age- and sex-matched non-diabetic subjects with or without…
To investigate the frequency and the biology of the metabolic syndrome in childhood cancer survivors in order to find risk factors for cerebro- and cardiovascular diseases and to design preventive intervention strategies in indicated risk groups
Primary objective: To investigate whether urine prothrombin fragments are increased in individuals suffering from VTE (i.e. PE or DVT) or a myocardial infarction compared to healthy matched controls.Secondary objective: to investigate whether…
- To detect carotid and aortic plaque morphology and long term plaque behaviour in patients with cerebral and cardiac end-organ damage (NSTEMI / STEMI and TIA / CVA) with 1.5T MRI-derived virtual histology and relation to biomarkers.- To correlate…
With this study we want to measure the two parameters who determine the hemodynamic status of the brain tissue. The first parameter we want to determine is the Cerebrovascular Reactivity (CVR), which is a measure for the degree in which blood…
To establish whether miRNA expression patterns in platelets, monocytes, plasma and endothelial cells differ between subjects with premature CVD and a positive family history of premature CVD as compared to age en sex matched healthy controls.