174 results
To investigate the effects of ICIs (anti-CTLA4, anti-PD1, combination anti-CTLA4/PD1) on vascular inflammation (PET-CT) in stage III melanoma patients. We hypothesize that the increase in vascular inflammation will be greater in the exposure group…
Investigate whether it is possible to detect plaque stabilization, determined by plaque stiffness, after a stroke or TIA with Ultra-COMPASS ultrasound measurements.
To determine the diagnostic performance of high-pitch CCTA and dynamic CTP for the diagnosis of myocardial ischemia using invasive coronary indices as the reference standard.
Rotating low-field MRI offers the opportunity to visualize the neck veins in different positions to study how these pathways differ with alternating body positions. For low-field MRI no standardized non-contrast-enhanced protocol is developed to…
AGELESS has 3 specific aims - they all refer to patients with carotid atherosclerosis:1. To compare patients with and without carotid intraplaque hemorrhage, as assessed with MR-Plaque Imaging, in terms of apoB, Lp(a) levels and traditional…
Primary objectives: To assess the extent of vascular wall inflammation in DM type 2 patients and the residual risk after 3 months of high dosage statin therapy, as measured with 68Ga-Dotatate PET-CT. Secondary objectives: To assess the feasibility…
The primary objective is to investigate the feasibility of NIR fluorescence imaging with intra-arterial ICG to detect differences in foot perfusion following successful endovascular lower extremity revascularization.
The primary objective of this study is to measure the number of antigen specific T-cells in the plaque and in blood, and investigate whether these parameters correlate with the phenotype of the atherosclerotic plaque. Secondary objectives are: 1) To…
The main objective of this study is to asses the applicability and validity of ICG parameters in the diagnostic work-up in patients with peripheral arterial disease. We will also asses the applicability of ICG-NIRF in intra-operative assessment of…
Several observational studies have been published evaluating DECTA for imaging of the lower legs, comparing this technique with conventional CTA. However, to the best of our knowledge, no randomised controlled trial has been conducted comparing both…
This is a safety and feasibility study to assess the technical use of a pressure guidewire and monorail infusion catheter to measure intracranial intra-arterial pressure and absolute flow.
This proof-of-concept study aims to prove the safety and feasibility of FFR in BTK lesions. Safety is defined here as conducting the FFR measurement without complications caused by the FFR measurement. Feasibility is defined here as successfully…
To investigate in a clinical study how often the use of intravascular optical coherence tomography for femoropopliteal stenotic lesions leads to alterations in treatment planning before and after stent placement, in comparison to traditional digital…
The main objective of the current study is to determine the feasibility of spatial and temporal quantification of swirling blood flow inside the SFA of patients treated with the BioMimics 3D stent, using high framerate (HFR) contrast enhanced…
The aim of this study is to assess the clinical value of bedside tests compared to DUS to detect PAD in patients with diabetes-related foot ulceration, with special emphasis on the ACCmax.
Assess the predictive capabilities of LSCI on the effect of endovascular revascularization on the microcirculation of the feet over time and what could this mean for clinical decision-making.
The primary aim of this study is to correlate regional muscle perfusion measured with [15O] H2O PET in patients with advanced PAD to local skin perfusion measured with TcPO2. Secondary objectives are to compare pre-revascularization perfusion rates…
See above.
Primary objective:To evaluate the performance of bST and echoPIV in quantifying spatiotemporal blood flow velocity profiles in the CA and SFA of healthy volunteers in comparison to 4D flow MRI.Secondary objective:- To determine the correlation of…
This proof of principle study aims to provide the safety and feasibility of OCT in patients with primary shunt failure requiring re-intervention. Safety is defined as conducting the OCT measurement without complications caused by the OCT measurement…