174 results
Primary Objective: 1. To determine the feasibility and clinical relevance of quantifiable parameters from intraoperative ALFA-measurements. Secondary Objective(s): 1. Determine the intraoperative applicability of ALFA. 2. Determine the effect of…
To assess the superiority of an IVUS-guided approach versus a qualitative angio-guided approach in patients with complex coronary lesions undergoing PCI.
To investigate the feasibility of skin perfusion measurements of lower limb tissue in 20 PAOD patients with continuous ICG-VA. Feasibility is defined as the ability to detect hypo perfusion in the diseased leg in comparison with the patient's…
1) To identify clinical and imaging predictors of recurrent stroke; 2) To improve early detection of small volume stroke with admission computed tomography perfusion (CTP) in patients with suspected acute ischemic stroke with small volume stroke or…
Primary Objective:To investigate whether arterial microcalcification (18F-NaF-PET detected) and macrocalcification (CT detected) are increased in patients with T2D who have macroalbuminuria as compared to patients with normoalbuminuria.Secondary…
This study aims to investigate the feasibility and clinical performance of tissue perfusion imaging with MSOT in the lower extremity of healthy volunteers, claudicants and patients with critical limb-threatening ischemia. The main objective is to…
This study has been transitioned to CTIS with ID 2024-512030-15-00 check the CTIS register for the current data. Our primary objective is to assess the effect of diltiazem on coronary microvascular function as assessed by coronary reactivity testing…
To study the effect of vitamin K supplementation on calcification propensity and vitamin K status in RTRs with vitamin K deficiency.
Primary: -The correlation between 18F-choline uptake in the atherosclerotic plaques on PET-MRI and plaque inflammation on histology, including the content of CD68-positive activated monocytes/macrophages.Secondary: -The correlation between the…
To test our hypothesis that vitamin K2 supplementation will induce a clinically relevant reduction in the degree of micro-calcification from carotid artery disease patients, when comparing to a placebo, after 3 months.
To assess the clinical outcome in NSTEMI and STEMI patients with vulnerable plaque characteristics in non-culprit vessels as assessed by OCT.
To validate 18F-Flutemetamol PET in the evaluation of plaque vulnerability.
Primary Objective:1. The primary objective is to investigate the level of agreement between scoring the presence of IPH on MR images acquired with MP-RAGE (conventional sequence) with scoring IPH on the multicontrast sequences. The level of…
The objective is to study reproducibility of the assessment of repetitive plaque deformation during the cardiac cycle in the carotid arteries by using advanced MRI techniques and state-of-the-art hardware.
The primary objective is validation of the MRA or CTA based personalized pre-procedural computer model, with intra-arterial pressure measurements at rest and during pharmacologically induced hyperemia, which serves as the gold standard.
Our main objective is to determine normal ranges for oxyhemoglobin, deoxyhemoglobin, oxygen saturation, local skin temperature and tcPO2 during all phases (pre-/per-/post-intervention) of treatment of peripheral arterial disease. Secondary…
To determine changes (i.e. pre- vs. postoperative) in 10-year cardiovascular disease (CVD) event risk according to contemporary widely applicable risk models in patients with CVD risk factors who have undergone intermediate-to-high-risk non-cardiac…
Hypothesis:We hypothesize that the combination of biomarkers (e.g. NT-proBNP, ST2, GDF15, Galectin 3, hsTn) is an early predictor of cardiac toxicity from radiotherapy and chemotherapy in a population at risk of developing late cardiac toxicity…
We hypothesize that intracranial vessel wall atheromas are an important underlying cause of obstruction of (one of the) artery(ies) of the anterior cerebral circulation. To test our hypothesis we will perform high resolution intracranial vessel wall…
The primary objective of the current study is to compare the presence or absence of arterial vessel wall abnormalities in the intracranial posterior circulation in patients with TIA or ischemic stroke with those of healthy controls using 7.0 tesla…