13 results
1). Evaluate the expression of the genes encoding the enzymes that modify histones and DNA during monocyte differentiation in MS.2). Consequences of monocyte dysfunction for migration and cytokine/chemokine production.
The aim of the study is to investigate the changes in peritoneal endothelial glycocalyx in end-stage renal disease (ESRD), with the duration of peritoneal dialysis, and relate these changes to alterations in peritoneal transport and morphology.…
The aim of this proposal is to investigate the potential use and value of experienced utility, as measured by the ESM and the DRM, in the economic evaluation of health care.Research question:1. What are the differences between the utilities measured…
Primary research question:To evaluate the impact of open versus endovascular invasive treatment in different types of surgery (AAA, CEA, LLR) on health status. Secondary research questions:To examine the prognostic impact of quality of life in PAD…
- To correlate clinical and biochemical cardiovascular risk factors to arterial wall 18-FDG uptake in large artery atherosclerotic lesions.- To correlate inflammatory markers to arterial wall 18-FDG uptake in large artery atherosclerotic lesions.
To examine whether a self-help psychological intervention program, based on relaxation, changing negative coping styles and finding new goals would be useful for people with PAD.
a) To investigate the differences in adipokines and inflammatory markers between obese and normal weight children; b) to study these differences over age, and c) to correlate adipokine/inflammatory marker profiles to clinical parameters for obesity…
The aim of this project is to study SNPs in genes involved in the cholesterol lowering pathway and in the anti-inflammatory pathway of statins to explain differences in the protective effect of statins against myocardial infarction (MI). A second…
1. To adjust and validate our forearm model for ischemia reperfusion injury, in order to used it for assessment of ischemic postconditioning.To adjust our forearm model for ischemia reperfusion injury, in order to used it for assessment of ischemia…
To assess intra- and interpatient variability of plasma Mg concentration before and after hemodialysis.
To assess the prevalence of LDL-C >1.8 mMol/L in a subgroup of very high risk patients with ASCVD, who remain at a very high-residual risk for ACS, despite treatment with high-intensity statins in combination with ezetimibe. This subgroup of…
Primary objective:- to compare the amount of contrast medium required to perform iliac/peripheral and EVAR procedures using the AlluraClarity control settings and the study settings, at similar procedure complexity, quantified as fluoro time, number…
The main objective is to investigate whether local mast cell activation correlates with an unstable phenotype of the atherosclerotic plaque.Secondary objectives are: 1. To investigate whether elevated systemic mast cell markers are correlated to…