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Lymph vessel mapping in femoropopliteal bypass surgery, a feasability study

To prove that lymph vessels in the legs can be visualized with methylene blue, so they can be spared during surgery, what possibly may lead to decreased postoperative lymph edema.Hypothesis: Methylene blue visualizes lymph vessels in the legs, so…

Molecular basis of lymphatic dysplasia in children

Our first aim is to find the cause of lymphatic dysplasia in children. The subsequent aim is to study the pathogenesis of the entity. The final aim is to increase our understanding of regulation of lymph vessel formation in man.

The impact of reconstructive breast surgery on the risk of developing lymphedema

Our primary objective is to determine the effect of breast reconstruction on the risk of developing lymphedema. Secondarily, we will look at lymphedema and the correlation with 1) primary and secondary breast reconstruction, 2) the extent of…

Treatment of breast cancer-associated lymphedema. A randomized study of the (cost-)effectiveness of manual lymphatic drainage and/or intermittent pneumatic compression

Objective of the study is to evaluate the different therapeutic options of lymphedema. Which treatment strategy is most cost-effective in the management of patients with breast cancer associated lymph edema: manual lymphatic drainage alone,…

The First Bratelle study, a prospective, single-arm, pilot study to confirm the efficacy of the Bratelle breast-pads, that has been experienced by a small group of individual patients, in a larger group and in a controlled setting.

Primary, improvement of the quality of life.Secondary, reduction of pain and a decrease of the number of treatments by a breast oedema therapist.