16 results
Study 1:1) To test the hypothesis that Liraglutide improves cardiovascular function in DM2 patients and whether the improvement is associated with redistribution of ectopic fat stores. 2) To test the hypothesis that Liraglutide activates BAT in DM2…
The objective of the study is to obtain information on the bioavailability and pharmacokinetics of the phenolics present in an olive leaf extract (Bonolive®, dose 250 mg), standardized on 40% oleuropein, and to identify the composition of the…
The objective of the study is to assess the impact of the physical form of five different cocoa matrices on the bioavailability of the monomeric flavan-3-ols. Assessment and evaluation will be done by comparing the kinetics of the main study…
The aim of this study is to investigate the effect of a MSE intervention on social participation and quality of life in chronic stroke patients. This MSE intervention will be compared to a controlgroup in order to measure the additional effect of…
The overall aim of the proposed research project is to investigate systematically the therapeutic potential of mental practice embedded in daily therapy on the improvement of daily activities of adult stroke patients compared to therapy as usual…
To evaluate the long-term clinical effectiveness of patients with IC randomized for supervised exercise training orendovascular revascularization.
The objectives are to explore in a step-wise approach the possibility to study reactive hyperemia and ischemia-reperfusion phenomena in humans by simultaneous assessment of vaso-reactivity and autonomous nervous system function.
The overall aim of the proposed research project is to investigate the therapeutic potential of mental practice embedded in daily therapy on the improvement in daily activities of adult patients with Parkinson*s disease and stroke patients. In the…
to investigate the safety and efficacy of idarucizumab in reversing the anticoagulation effect of dabigatran, in patients who have uncontrolled bleeding or require emergency surgery or invasive procedures.
See section 2.2. of the protocol.The primary objective of this trial is to assess the safety of an uninterrupted dabigatran etexilate periprocedural anticoagulant regimen compared to an uninterrupted warfarin regimen in NVAF patients undergoing AF…
This study will assess the patient* health status regarding vascular symptoms after TF-AVI procedure together with stent function and the rate of stent fractures
The objective of this study is to assess the safety and effectiveness of the COVERATMObjectives: Vascular Covered Stent for the treatment of stenotic lesions in the upper extremityvenous outflow of the AV access circuit.
To investigate whether the collagen-based MANTA vascular closure device (VCD) is superior to suture-based VCDs in preventing vascular access site complications in patients undergoing transfemoral transcatheter aortic valve replacement.
the primary aim is to determine the effect of thawed deep-frozen platelets re-suspended in thawed deep-frozen plasma versus room temperature stored platelets in platelet additive solution for transfusion on the percentage of patients with surgical…
Primary objective: to study whether pyridoxamine supplementation in type 2 diabetes improves microvascular function in the eye, kidney and skin, and reduces markers of endothelial dysfunction and glycation.Secondary objective: to study whether…
To evaluate if balloon pulmonary angioplasty (BPA) is non-inferior to pulmonary endarterectomy (PEA) in patients with chronic thromboembolic pulmonary hypertension (CTEPH) who are eligible for both treatments.