14 results
The primary objective for this study is to evaluate the cerebrovascular reactivity of HCHWA-D patients:1. To compare the (autoregulatory) function of small brain vessels in HCHWA-D patients with matched controls using the cerebrovascular reactivity…
The general aim of this study is to implement validated markers for CAA in asymptomatic individuals with CMBs, to investigate whether presence of CMBs signifies early CAA.
The main object is to evaluate the validity of a diagnostic screening package for bleeding tendency consisting of point-of-care devices when compared with the gold standard for bleeding tendency diagnosis.Other objects which will be investigated are…
To demonstrate that MRI is as good in the detection of clinically relevant PAVM as the CT.
The purpose of this study is to gain insight into the effects of auditory pacing on the stability and flexibility of hemiplegic gait coordination. It will be examined how auditory pacing can be best administered to improve the quality of hemiplegic…
The aim of this study is to determine the concurrent and divergent validity of the Actiwatch method in patients with subacute and chronic stroke.
To assess the validity, reliability and feasibility of accelerometers and the Pedar Mobile system for measuring balance during standing and walking of patients with neurological and vestibular disorders.
1- to describe the presence and severity of hemiplegic CP on the basis of neonatal MRI findings and correlate the involvement of different structures (basal ganglia, posterior limb of the internal capsule and hemisphere) with the size of the lesion2…
Objective and Research QuestionsTo identify predictors of brain outcomes in HHT patients, we propose to leverage our multicenter network of HHT Centers to characterize comprehensive brain outcomes.Study Aims:Aim 1: We hypothesize that the presence…
To evaluate early cerebral perfusion changes of the ischemic brain after IVT and/or EVT in relation to progression of infarct core assessed by arterial Spin Labeling perfusion MRI.
To investigate longitudinal changes in VR in patients with subjective cognitive impairment (SCI), mild cognitive impairment (MCI) and AD dementia compared with controls. To investigate whether VR predicts progression of disease severity (cognitive…
To determine the effectiveness of more intensive BP lowering provided by a *Triple Pill* strategy on top of standard of care, on the time to first occurrence of recurrent stroke after ICH.
Objective: 1. To determine whether vascular reactivity is lowered in memory clinic patients with mixed and pure AD pathology. 2. To define whether vascular reactivity upon visual activation is associated with CAA or with other small vessel disease (…
Primary objective: describe the longitudinal changes of Aβ38, Aβ40, Aβ42, and Aβ43 concentrations in CSF of patients with CAA, AD, and healthy control cases and estimate the differences in change between those groups.1. Explorative study to…