9 results
1) To determine if microinfarcts can be detected in the brain with 7T MRI in AD patients2) To determine the prevalence and number of cerebral microbleeds on 7T MRI in patients with AD and to relate these lesions to cognition and to the vascular risk…
The overall aim of this study is to investigate the pathophysiology of ICH by investigating intracerebral hemorrhage in HCHWA-D patients. By investigating triggers for ICH, hematoma expansion, recurrence rate and outcome in HCHWA-D related ICH we…
Primary Objective: 1) To charaterize microbleeds and microinfarcts at 7T, and compare their prevalence in people with and without diabetes, with or without cognitive impairmentSecondary Objective(s): 2) To assess the relevance of the lesions in the…
Primary Objective: 1) To compare the prevalence en number of microbleeds at 7T between older people with and without DM2, and to relate the lesions to cognitive performanceSecondary Objective(s): 1) To characterize cerebral microinfarcts at 7T and…
The primary objective is to evaluate longitudinal developmental changes in brain structure in patients aged 6-18 years with SCD. The secondary objective is to analyze the longitudinal relations between biomarkers, demographic characteristics, brain…
Primary Objective (PHASE 1: feasibility study): - Determine whether measurements of glycocalyx and other microvascular parameters using SDF imaging (on the conjunctiva and sublingually) are feasible in aSAH patients during a period of 2 weeks post-…
The main objective is to examine determinants of physical behaviour in patients with SAH (primary in patients with A-SAH and secondary in patients with PM-SAH). Secondary, preferences of patients for therapy to reduce fatigue will be explored in…
1. To investigate the size of the HCHWA-D population by identifying all (possible) mutation carriers and their relatives. 2. Study the genealogy and natural disease history of these carriers.3. Get insight in possible genetic, environmental and…
To determine whether serum soluble VEGFR1 is also reduced in HHT2 patients and might be used as marker of disease severity.