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A Phase 2, Multicenter, Blinded, Sham Procedure-Controlled Trial of Renal Denervation by the Peregrine System Kit, in Subjects with Hypertension, in the Absence of Antihypertensive Medications

Approved WMOCompleted

The current proof-of-concept study has been designed to assess the efficacy and safety of the Peregrine Kit in the treatment of subjects with hypertension, when discontinued from their antihypertensive medications. This will be an *off medication*…

A Pivotal, Multicenter, Blinded, Sham Procedure-Controlled Trial of Renal Denervation by the Peregrine System* Kit, in Subjects with Hypertension.

Approved WMORecruiting

This study has been transitioned to CTIS with ID 2024-512525-83-00 check the CTIS register for the current data. Primary Objective (Randomized Controlled Trial [RCT] Cohort): to evaluate the efficacy of renal denervation by alcohol-mediated…

STEPWISE treatment of uncontrolled HyperTensioN in primary care: a cluster randomised trial.

Approved WMORecruitment stopped

The objective is to investigate whether application of a stepwise work-up strategy in primary care patients with uncontrolled hypertension results in better blood pressure control in a cost-effective manner.