28 results
We want to demonstrate or exclude through this study that the administration of a dilute anesthetic solution, using local tumescent anesthesia technique, will lead to a significant decrease in per-and postoperative pain in patients undergoing…
Our study tries to identify the ideal sclerosant dosage for the ClariVein® system in order to occlude the GSV permanently. By choosing the lowest dose with the same anatomical success rate, we achieve a safe treatment which also gives us the…
To evaluate whether no utilization of compressive stockings is as effective as wearing a Class II Thrombo Embolic Deterrent (TED) stocking for 4 hours. Primary outcome is leg volume on post-operative day 14.The secondary objective is to study the…
Objective: To evaluate the anatomical success of MOCA versus RFA in treatment of symptomatic insufficient SSV.
The goal of this registry study is to provide insight in the safety and efficacy of treatment with MOCA for primary insufficiency of the GSV with a diameter >/=12mm, insufficient antero-lateral branches (<12 mm) and insifficincy of the…
The Clari-laser study is designed to evaluate the following questions: 1. What is the succes rate of MECEA versus EVLA on short and long term? 2. Are the results after treatment both clinically and technically comparable? 3. What are the per-and…
Primary:- to assess the multiple-dose pharmacokinetics of apixaban and rivaroxaban - to compare plasma concentration peak to trough ratio (Cmax/Cmin) of rivaroxaban to apixaban Secondary:- to assess the multiple dose pharmacodynamics (anti-Factor Xa…
We want to investigate the patient satisfaction after both treatments and differentiation in direct costs between the radiofrequency ablation (by VNUS closureFAST) and treatment with the radial fiber 1470 nm endolaser. We want to compare both…
To date, all studies evaluating minimally invasive interventions for treatment of venous insufficiency of the GSV have been comparing the techniques to the traditional method of stripping (under spinal or general anesthesia, without using duplex…
This study will determine the concentration of benzo[a]pyrene before and after EVLA.
To test whether the anatomical success rate of Steam Ablation is not inferior to that of VNUS in treatment of GSV insufficiency and compare the treatment safety, patient reported outcomes between and Steam Ablation.
5.1 Study ObjectivesThe primary objective for this clinical observational study is to assess the role of the Sapheon Closure System in closure of incompetent great saphenous veins in a routine clinical setting.5.2 Study HypothesisThis is an…
To compare the success rate and the occurrence of complications of re-crossectomy and (repeated) UGFS for the treatment of recurrence of the SSV for a period of 5 years.
Analysis of short and long term results of stripping and endovenous laser treatment for long saphenous vein incompetence under local anaesthesia.Endpoint is the recurrence rate of the varicose vein, secondary endpoints are pain, complications,…
This study aims to show by which technique the patient feels the least pain. It is also designed to show which advantages and disadvantages are linked to the abovementioned forms of anesthesia and if there are differences in postoperative pain…
The main objective is to determine whether the post-operative application of elastic stockings after varicose vein surgery is useful to reduce post-operative pain. Secondly we want to determine whether there is a difference in physical functioning…
To test whether the anatomical success rate of Steam Ablation is not inferior to that of EVLA in treatment of GSV insufficiency and compare the treatment related complications, patient reported outcomes and cost-effectiveness analyses between EVLA…
Comparing the gold standard of surgical stripping with the minimal invasive treatment options: laser and VNUS (radiofrequency ablation)
A randomized comparative study of the treatment of the insufficient greater saphenous vein: crossectomy with short strip vs Ultrasound guided foam sclerosis vs endovasculair laser. The Magna trial. The emphasis of this study will be on comparing the…
The objective of the study is to evaluate the clinical efficacy of 3M* Coban* 2 Layer Compression System in the treatment of venous leg ulcers compared to Rosidal® K shortstretch compression bandage (Lohmann & Rauscher, Rengsdorf, Germany).