136 results
The main objective of this pilot study is to determine the effects of vascular access construction on autonomic and cardiac function.
In this study one of the goals is to compare 7 tesla MRI with 3 tesla MRI in terms of lesion detection in epilepsy patients and depiction of specific dysplasia-related imaging characteristics. Furthermore, resected tissue will be scanned ex-vivo at…
1. Immunology and Pathology:To determine the immune response of patients with simple and complex appendicitis in order to identify markers which distinguish between simple and complex appendicitis.2.Clinical and Imaging:To analyze the differences in…
To study the effect of a nerve block of the infrapatellar nerve with local infiltration with lidocaine or saline on chronic anterior knee pain after tibial nailing.Secondairy objectives:- to measure knee pain on a VAS for eight different activities…
1. To get new insights in the pathophysiology of PPS by comparing tissue characteristics (histology) of the pericardium in patients with and without PPS. 2. To identify biomarkers that are associated with PPS by collecting 4 blood- and 1 pericardial…
With this study we aim to elucidate the effects of HBOT on the oral microcirculation in patients with malignant disease in the head and neck region after receiving radiotherapy (RT). We want to test the hypothesis that HBOT improves RT-induced…
We are performing a large randomised trial of *deep* versus *light* anaesthesia to definitively answer the question of whether anaesthetic depth alters perioperative outcome. Elderly patients undergoing major surgery will be randomised to an…
The primary objective is to investigate the determinants of aortic root deformation occurring >= 3 months after successful ASO implantation in adult patients with an atrial septal defect.
The aim of this study is to identify Galectin-1 and -3 as possible biomarkers in capsular contracture. Moreover, we plan to investigate whether HLA-typing and IgE levels in subjects can be used to predict the chance of development of capsular…
The aim of this project is to elucidate how corticosteroids protect cardiac surgical patients from PNAF. We will therefore examine the modulating effect of prophylactic high-dose corticosteroid administration on perioperative risk factors for PNAF.…
In this study the effect of the pneumoperitoneum on the intestine of children is objectified by measuring the iFABP levels in the urine, as an indicator for the ischemia or damage to the intestine. To exclude any iFABP increase due to intestinal…
First, to determine the extent to which microcirculatory perfusion defects occur during clinical kidney transplantation. Second, to study the relationship between these events and kidney function, inflammation and renal cellular injury. Third, to…
Primary Objective: 1. A search for (objective) EEG predictors (independent variables) for both acute and chronic postoperative pain (dependent variables) after breast cancer surgery. The EEG variables are derived from the above mentioned five…
Primary Objective: To determine the local and peripheral immune response in diabetic pregnancies in comparison to healthy controls. Immune response will be measured by counting Th1/Th2-cells, Tregs, NK-cells, monocytes and granulocytes. Produced…
To identify predictive variables correlated with percentage excess weight loss, reversal of metabolic complications of obesity and quality of life and postoperative complications; to identify metabolic variables correlated with markers of the…
1. To compare the induction of a procoagulant state between patients undergoing PVI using the PVAC catheter, the cryoballoon catheter or the cooled tip catheter.2. To compare the incidence of CE on diffusion weighted MRI between the three groups of…
In a randomized controlled trial, the effects of DHCA and ACP during complex neonatal cardiac surgery on organ function and injury will be compared, especially focusing on cerebral damage and neurological outcome. The primary research question is…
primary objective:-to define the optimal glucose intake by quantifying endogenous glucose production and fractional gluconeogenesis in critically ill children.secundary objectives:-determine glucose utilization in relation with exogenous glucose…
The primary objective in this study is to detect the presence of supra-spinal central sensitization in patients with chronic neck pain secondary to cervical facetal arthropathy. We aim to show this by comparing the pressure-pain thresholds (PPT; the…
1) To investigate what changes are present in skeletal muscle tissue of elderly gastric and colonic cancer patients (>80) compared with younger gastric and colonic cancer patients (<60) and compared to elderly controls and younger…