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The ClariVein device using 2% and 3% liquid Polidocanol for the treatment of great saphenous vein incompetence

Our study tries to identify the ideal sclerosant dosage for the ClariVein® system in order to occlude the GSV permanently. By choosing the lowest dose with the same anatomical success rate, we achieve a safe treatment which also gives us the…

Endovenous laser ablation versus mechano-chemical endovenous ablation in the treatment of great saphenous incompetence: a multicentric, randomized controlled trial

The Clari-laser study is designed to evaluate the following questions: 1. What is the succes rate of MECEA versus EVLA on short and long term? 2. Are the results after treatment both clinically and technically comparable? 3. What are the per-and…

A randomized European Study Comparing Endoluminal Stent grafting and best medical Therapy (BMT) to BMT Alone in the Traetment of Acute Uncomplicated Type B Aortic Dissection

Objective of the study: The primary objective of this study is to assess the efficacy See primary endpoints, section 7.1 of endoluminal stent grafting and BMT compared to BMT alone in the treatment of uncomplicated acute type B aortic dissections.

Perioperative esmolol infusion for haemodynamic stability during major vascular surgery.

Primary Objective: comparing hemodynamic stability provided by titration of esmolol in addition to standard perioperative care including low-dose metoprolol to placebo and standard care.Secondary Objective(s): -comparing the incidence of…

CABG Off or On Pump Revascularization Study (CORONARY) - a randomized multicenter study

Therefore, there is a real need for a trial to reliably evaluate the short and long term safety and efficacy of off-pump CABG. From a clinical point of view, it is essential to determine if off-pump CABG is associated with a reduction in major…

Randomized Evaluation of dabigatran etexilate Compared to warfarIn in pulmonaRy vein ablation: assessment of an uninterrupted periproCedUral alntIcoagulation sTrategy (The RE-CIRCUIT Trial)

See section 2.2. of the protocol.The primary objective of this trial is to assess the safety of an uninterrupted dabigatran etexilate periprocedural anticoagulant regimen compared to an uninterrupted warfarin regimen in NVAF patients undergoing AF…

The Rotterdam Antiplatelet Therapy in Vascular Patients Study

The objective of the proposed study is to evaluate if results as are written above, are to be extrapolated on high risk patients who underwent vascular surgery. In this group of patients, there is a substantial risk of 15-20% to die in the first…

DIStal versus COnventional RADIAL access for coronary angiography and
intervention: a randomized multicenter trial

The objective of this study is to demonstrate the superiority of Distal Transradial Access (DTRA) to Conventional Transradial Access (CTRA) regarding forearm radial artery occlusion (RAO) using the 6Fr Glidesheath Slender (GSS).

EXpansion of stents after Intravascular lithoTripsy versus conventional predilatation in CALCified coronary arteries

To compare stent expansion after plaque modification by IVL or balloon predilation in severely calcified coronary lesions assessed by optical coherence tomography (OCT).

A randomized controlled trial comparing venous stenting with conservative treatment in patients with Deep Venous Obstruction

Primary Objective: Measure QoL (VEINES QoL/Sym) change in patients with DVO at one year after PTA and stenting compared to conventional therapy (short class II elastic compressions stockings, exercise, lymph drainage therapy and the use of (pain)…

Axis for Ultrasound guided Venous Access

To identify whether a short axis approach (SAA) or a long axis approach (LAA) to ultrasound guided peripheral cannulation is superior when performed by ED nurses without prior ultrasound experience.