81 results
The aim of this study is to objectify nipple-areola complex sensitivity in women who underwent unilateral or bilateral prophylactic NSM in Erasmus MC-Daniel den Hoed Cancer Center and their satisfaction with this operation, compared to healthy women…
The objective of the study is to assess which outcomes are most important to patients, so that we can inform them better and contribute to decision making. If patients, depending on treatment or age, consider PROMSs more or less important than…
The BASIS study will analyze the full cancer genome of breast cancer subtype ER+ HER2-.
Our primary objective is to determine the effect of breast reconstruction on the risk of developing lymphedema. Secondarily, we will look at lymphedema and the correlation with 1) primary and secondary breast reconstruction, 2) the extent of…
This study investigates 3 different aspects of RFA treatment:1. Feasibility and safety of RFA treatment in elderly patients ( > 70 years) with T1 breast carcinoma who are not or less fit for surgery.2. Efficacy of RFA treatment in elderly…
MULTICENTER FEASIBILITY STUDY OF THE SENTINEL NODE PROCEDURE IN PATIENTS WITH MULTIPLE BREAST TUMORS
The aim of the study is to validate the sentinel node procedure in breast cancer patients with multiple tumors and to investigative whether an intratumoral injection of the radiopharmaceutical in each tumor will result in additional sentinel nodes…
proof of safety of the Style 410 silicon breast implants
Detection of breast carcinoma with an ICG enhanced optical imaging device in breast cancer patients.
Ergonomics and function of the imaging system - the NIRF imaging system should not interfere with the standard lumpectomy procedure and used safely by the surgeon while detection of ICG within the tumour takes place. Duration: 1,5 hour clinical…
Primary objective is to investigate whether palliative pleurectomy / decortication after 4-6 courses of standard chemotherapy with cisplatin and pemetrexed will lead to a doubling of the overall survival compared to a control group which will…
The aim of this study is to investigate the effect of incorporating a CT-thorax in the target volume delineation process on 1) percentage of the target volume that receives less than 85% of the prescribed dose, 2) the size of the irradiated boost…
Riskreduction of developing breast carcinoma by means of better surgical techniques (removing all normal breast tissue).
Interactive provision of information with the use of web-based applications should increase patient satisfaction, which is an important performance factor. This information should be consistent and clear for the patient. Patient satisfaction is…
To test the hypothesis stated above, we propose to study the dose-response relationship between various chemostimulants and PMN functions of major trauma patients and patients undergoing major surgery in vitro, both early after the initial trauma or…
Investigate the consequences of axillary lymph node dissection (ALND) and sentinel lymph node procedure (SNP) regarding shoulder impairments, the activities a women still undertakes and the role of quality of life and anxiety in this in women who…
An efficiency study will be conducted to evaluate the systematic use of the distress thermometer and its discussion by a nurse as compared to the usual care provided to outpatients who are treated for primary breast cancer by their treating…
The proposed study will focus on newly diagnosed breast cancer patients who, prior to receiving treatment, are identified on the basis of age or family history of breast or ovarian cancer as having at least a 10% risk of carrying a mutation in the…
The aim of this study is to compare the clinical outcome and survival in patients undergoing sternal closure treatment or conventional treatment for postoperative mediastinitis. The secondary objective is to determine incidence of mediastinitis and…
The primary aim of this study is to prospectively assess the incidence of pulmonary embolism in patients undergoing abdominal flap breast reconstruction.
Pilot for determining the feasibility and image quality of high resolution Tc99m-SestaMIBI imaging of lumpectomy specimens for detection, localization, and quantification of resection margins.
The main objective of this study is to define the optimal dose of fluorescent tracer for intraoperative detection of tumor delineation during breast cancer surgery.