49 results
The purpose of this clinical study is to investigate surgical usability, patient-reported outcomes and effectiveness of the MaMaLoc technique and compare it with WGL.
The study aim is to decrease the number of breast cancer patients receiving overtreatment of the axilla, in order to positively influence the axillary morbidity rate and quality of life. Therefore, we investigate whether completion axillary…
To determine the resorption of ropivacaïne and serum concentration we need 6 bloodsamples at t=0, t=30 min, t=1 hour, t=2 hour, t=4 hour, t=8 hour. A pharmacokinetic model will be made for each procedure using a software package MW/Pharm © (version…
In this study we will evaluate the possibility to locally ablate small breast carcinomas with RFA. Finally this study should contribute to the replacement of the conventional lumpectomy by RFA.1) Can radiofrequency ablation (RFA) completely destroy…
Primary Objective: The primary objective of the present study is to assess the feasibility of using the declipseSPECT system for accurate I-125 seed localisations in breast cancer surgery.Secondary Objective(s): • Assess the accuracy of I-125 seed…
A novel one-stage procedure where definitive implants are combined with a collagen matrix is compared to the traditional two-staged procedure where a tissue expander is placed before an implant. Our hypotheses are the following:The use of a collagen…
Aim of the study is to compare the efficacy and safety of the use of a low vacuum constant drainage system (Palin®) with a high vacuum closed suction drainage system (Medinorm S-400®) after chest wall masculinization in female-to-male transgenders.
We hypothesized that obliteration of the dead space following mastectomy would significantly reduce seroma formation and therefore seroma related wound complications and patient discomfort (fewer seroma aspirations and fewer check ups in the out…
The aim of this study is to compare clinical outcomes and cost-effectiveness of two procedures for skin sparing mastectomy with implant reconstruction in a randomized clinical trial. The customary method for one-stage breast reconstruction with…
To reduce the extent of healthy breast tissue resection by US-guided surgery for palpable tumours compared to traditional palpation-guided surgery, without compromising oncological principles. To improve cosmetic outcomes and quality of life by US-…
To evaluate the efficacy of ROLL versus WGL in breast conserving surgery for non-palpable breast cancer.
The main objective of this feasibility study is to assess the treatment accuracy of MR-HIFU in patients with breast cancer using a dedicated MR-HIFU breast system. A secondary objective is to determine the safety.
The aim of this study is to objectify nipple-areola complex sensitivity in women who underwent unilateral or bilateral prophylactic NSM in Erasmus MC-Daniel den Hoed Cancer Center and their satisfaction with this operation, compared to healthy women…
This study investigates 3 different aspects of RFA treatment:1. Feasibility and safety of RFA treatment in elderly patients ( > 70 years) with T1 breast carcinoma who are not or less fit for surgery.2. Efficacy of RFA treatment in elderly…
proof of safety of the Style 410 silicon breast implants
Primary objective is to investigate whether palliative pleurectomy / decortication after 4-6 courses of standard chemotherapy with cisplatin and pemetrexed will lead to a doubling of the overall survival compared to a control group which will…
The aim of this study is to investigate the effect of incorporating a CT-thorax in the target volume delineation process on 1) percentage of the target volume that receives less than 85% of the prescribed dose, 2) the size of the irradiated boost…
The aim of this study is to compare the clinical outcome and survival in patients undergoing sternal closure treatment or conventional treatment for postoperative mediastinitis. The secondary objective is to determine incidence of mediastinitis and…
The main objective of this study is to define the optimal dose of fluorescent tracer for intraoperative detection of tumor delineation during breast cancer surgery.
the aim of this prospective cohort study is to investigate the difference in quality of life and satisfaction with cosmetic result in patients with breast cancer undergoing breast conserving therapy surgery versus patients undergoing breast…