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Long-term results of two-stage breast reconstruction with polyurethane-covered versus textured implants: a prospective, multicenter randomized controlled trial

Primary Objective: to determine whether polyurethane covered silicone implants (PCI) give a different capsular contracture rate than textured silicone implants (TI) in two-stage implant breast reconstruction after mastectomy in women.Secondary…

Pilot study on the use of a radiopaque hydrogel during breast conserving surgery with full-thickness closure for target definition and positioning of boost or partial breast irradiation.

Primary objective: Estimate the Conformity Index (Cx) of target definition. Secondary objectives: Estimate the distance between the center of mass (dCOM) of the observers* target volumes, Cavity Visualisation Score (CVS), feasibility of the hydrogel…

The treatment of breast cancer with thermal ablation: a pilot study

The primary objective is to investigate if thermal ablation of breast tumors less than 2cm with < 25% DCIS is effective in terms of the number of tumors in which complete ablation is found on pathology result.

Effects of discharge with drain in situ on the risk of infection after placement of a tissue expander.

The primary objective of the study is to objective if there is a greater risk of loss of the tissue expander due to infection if patients are discharged with a surgical drain in situ.

Seroma reduction and drain free mastectomy - SARA trial

To prove that omitting drains after mastectomy and flap fixation does not contribute to higher incidence of seroma formation and therefore reducing patient disutility such as seroma aspirations and visits to the outpatient clinic, as well as…

Using optical spectroscopy for the detection of positive resection margins for invasive ductal carcinoma and ductal carcinoma in situ during breast conserving surgery

To assess the sensitivity and specificity of optical spectroscopy for the detection of Invasive Ductal Carcinoma (IDC) and Ductal Carcinoma In Situ (DCIS) deposits on resection margins during breast conserving surgery.

A randomized controlled trial testing hyaluronic acid spacer injection for skin toxicity reduction of Permanent Breast Seed Implant (PBSI)

The primary objective is to evaluate and report the effect of an injected hyaluronic acid spacer on the rate of telangiectasia following PBSI.

Breast conserving therapy using Accelerated Partial Breast Irradiation (APBI) in elderly patients: a feasibility study

Confirm favorable treatment results of international studies.Relate (loco regional) tumor control, side effects and (inter current) death to geriatric questionnaires/condition, co-morbidity and usage of medication.

A radiopaque hydrogel to improve target definition of boost or partial breast irradiation in patients with low cavity visualization scores

Primary objective: Estimate the added value of using hydrogel in addition to clips only in terms of the Conformity Index (Cx) of tumorbed delineationSecondary objectives: Estimate the Cavity Visualisation Score (CVS), distance between the center of…