24 results
The aim of this study is to investigate the host tissue response to the implanted collagen inlay in implant based breast reconstruction. Secondary, we want to investigate if the presence of capsular formation is associated with the presence of…
The principal objective of the study is to determine if the performance of the new technique (magnetic tracer and magnetometer) is equivalent to the performance of the standard technique (patent blue dye and radioisotope, wire localization).The…
To measure the wavelength dependent differences in optical properties between normal and malignant breast tissue over a broad wavelength range (400-1000 nm).
To evaluate the tissue-oxygenation and microcirculation before, during and after application of artificial pneumoperitoneum/-thorax using Near Infrared Spectroscopy (NIRS) and Sidestream Dark Field Imaging (SDF) and validate the usefulness of these…
The objective of this study is to determine the accuracy of the sentinel lymph node biopsy in multicentric breast cancer prospectively and multi-institutional.
Pilot for determining the feasibility and image quality of high resolution Tc99m-SestaMIBI imaging of lumpectomy specimens for detection, localization, and quantification of resection margins.
This study aims to develop a prediction rule for PMPS one year after breast surgery based on neurophysiological, psychological, and clinical parameters. Based on this prediction, individualized perioperative management and postoperative revalidation…
Primary Objectives: Investigate whether the usage of pre-operative projections prior to a deep inferior epigastric perforator flap breast reconstruction leads to more correctly identified perforator locations and less operation time spend on…
MULTICENTER FEASIBILITY STUDY OF THE SENTINEL NODE PROCEDURE IN PATIENTS WITH MULTIPLE BREAST TUMORS
The aim of the study is to validate the sentinel node procedure in breast cancer patients with multiple tumors and to investigative whether an intratumoral injection of the radiopharmaceutical in each tumor will result in additional sentinel nodes…
Detection of breast carcinoma with an ICG enhanced optical imaging device in breast cancer patients.
Ergonomics and function of the imaging system - the NIRF imaging system should not interfere with the standard lumpectomy procedure and used safely by the surgeon while detection of ICG within the tumour takes place. Duration: 1,5 hour clinical…
Interactive provision of information with the use of web-based applications should increase patient satisfaction, which is an important performance factor. This information should be consistent and clear for the patient. Patient satisfaction is…
The principal objective of the study is to determine if the performance of the new technique (magnetic tracer and magnetometer) is equivalent to the performance of the standard technique (patent blue dye and radioisotope; or radioisotope alone).The…
Research question: Is microbubble-enhanced Iodine-125 seed localization an accurate tool for preoperative identification of the sentinel lymph node in women with breast cancer, in terms of diagnostic accuracy, sensitivity, feasibility, patient…
Up front breast surgery in patients with primary distant metastatic breast cancer, will result in an improvement of the 2-year survival compared to the survival achieved with systemic therapy and delayed local treatment or systemic therapy alone.The…
The primary objective of this study is to analyse the feasibility and internal validity of Magtrace in the sentinel node procedure in breast cancer in the Breast Care Centre in Zuyderland Medical Centre; with the ultimate goal to make the sentinel…
The value of implementation and cost-efficacy of Tumor Volume / Breast Volume Ratio, as measured by Automated Breast Volume Scanner (ABVS), during the preoperative workup in breast cancer patients on 1) cosmetic result after BCS, and 2) surgical…
To assess whether core biopsies of the breast after neoadjuvant chemotherapy can reliably predict a pathologic complete response. We will therefore calculate the sensitivity, specificity, positive predictive value and negative predictive value of…
The main goal of this study is to examine the accuracy (identification rate of the MARI-node and Sentinel node, sensitivity, negative predictive value (NPV) and false-negative rate (FNR)) of the RISAS procedure compared to the current standard…
The primary objective is to assess the feasibility of intraductal biopsy and intraductal laser ablation in patients with intraductal lesions. Secondary objectives are: treatment success of interventional ductoscopy (biopsy and laser ablation) in…
This study is designed as a single-center diagnostic accuracy study. The duration of the study is 2 years. To introduce tissue sensing during the stereotactic VABB, we developed an optical introducer with DRS fibers that can be integrated with the…