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Assessing and predicting functional and quality of life-related outcomes of islet and pancreatic transplantation in patients with type 1 diabetes mellitus

There are two objectives for this study: first, to find specific serum beta cell damage markers that can serve as a clinical predictive tool for beta cell allograft loss. Second, to compare quality of life and diabetes-related outcomes in patients…

Radioactive iodine treatment versus hemithyroidectomy in patients with symptomatic benign euthyroid goitre

To compare the effect of radioactive Iodine or hemithyroidectomy on the symptoms and quality of life (QoL) of patients with a benign euthyroid goiter.

Prophylactic abdominal drainage or no drainage after distal pancreatectomy: a binational multicenter randomized controlled trial

To evaluate the non-inferiority of omitting routine intra-abdominal drainage after distal pancreatectomy on postoperative morbidity (Clavien-Dindo score >= 3), and, secondarily, POPF grade B/C.

Focus on values to stimulate shared decisions in patients with thyroid cancer: A multifaceted
COMmunication BOoster (COMBO)*

Aim: to develop, implement and evaluate COMBO to improve SDM during the treatment trajectory of TC patients in situations when clear cut recommendations cannot be made either because the benefits closely balance with risks, or because this balance…