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Does a decision aid improve decision making in prosthetic heart valve selection?

Conduct a multicenter randomized clinical trial to assess whether the use of the decision aid results in optimization of shared-decision making and improved quality of life in patients who have been accepted for aortic and/or mitral valve…

Microcirculatory changes during cardiac surgery: The effects of different modalities of cardiopulmonary bypass

Does CPB affect microcirculatory function by comparing on-pump (CON-CPB) and off-pump (OFF-PUMP) cardiothoracic surgery?Does pulsatile flow during cardiopulmonary bypass (PULSE-CPB) improve microcirculatory function as compared to continuous flow (…

Pilot study: A comparison of the extent of haemolysis induced by conventional versus miniaturised extracorporeal circulation during coronary artery bypass grafting surgery, and the influence on the release of damage associated molecular patterns (DAMPs), leukocyte activation and neutrophil extracellular trap (NET) formation.

Primary Objective: To compare the extent of haemolysis associated with the use of the conventional versus the miniaturised heart lung machine in the Amphia hospital, with the aim to set up evidence-based guidelines for the use of a specific type of…

The CRYSTAL study: CMR of intraventricular flow analysis and genetic phenotyping in Hypertrophic Cardiomyopathy (HCM): a roadmap for surgical myectomy

The primary objective of this study is to assess wall shear stress in the left ventricle outflow tract using 4D flow CMR in healthy controls, asymptomatic HCM and before and after surgical myectomy in patients with HOCM,