133 results
Conduct a multicenter randomized clinical trial to assess whether the use of the decision aid results in optimization of shared-decision making and improved quality of life in patients who have been accepted for aortic and/or mitral valve…
The aim of this project is to elucidate how corticosteroids protect cardiac surgical patients from PNAF. We will therefore examine the modulating effect of prophylactic high-dose corticosteroid administration on perioperative risk factors for PNAF.…
Our primary objective is to evaluate the effect of perioperative enteral and parenteral nutrition on amino acid profile and cardiomyocytes functioning in the cardiac surgical patient. Our secondary objective is to study the effect of the (par)…
The PAPPA-trial was the first prospective clinical study the feasibility and safety of a DEB only strategy in PPCI for STEMI. One-year angiographic follow-up is warranted to evaluate long-term patency of the target lesion. So far there has not been…
In a randomized controlled trial, the effects of DHCA and ACP during complex neonatal cardiac surgery on organ function and injury will be compared, especially focusing on cerebral damage and neurological outcome. The primary research question is…
1. To compare the induction of a procoagulant state between patients undergoing PVI using the PVAC catheter, the cryoballoon catheter or the cooled tip catheter.2. To compare the incidence of CE on diffusion weighted MRI between the three groups of…
The aim of this study is to evaluate the safety and feasibility of postoperative pericardial perfusion with (prewarmed NaCl 0.9%) and the effect of perfusion on blood loss after cardiac surgery. Hypothesis Pericardial perfusion with (prewarmed NaCl…
This study will test the hypothesis that acute administration of statins will provide for a better protective (anti-inflammatory) effect than chronic administration. Patients used for this study have to undergo mitral and/or tricuspid valve surgery…
The goal of this study is to determine if off-pump CABG surgery is associated with better cerebral tissue oxygenation when compared with on-pump CABG. In addition, we would like to compare the results of two different monitors of brain tissue…
To determine if aspiration thrombectomy can reduce the rate of cardiovascular death, recurrent myocardial infarction, cardiogenic shock, or new or worsening NYHA Class IV heart failure in patients with STEMI undergoing primary PCI.
To determine the effects of surgical trauma on heparin sensitivity and hemostasis during coronary artery bypass grafting (CABG) and cardiac valve surgery.To determine the relation between hemostatic activation and the heparin dose responsiveness as…
Fontan circulation: Analysis of its Impact on quality of life and Rate of deterioration (FAIR study)
Primary Objective: - Investigating the rate of the attrition and predictors of the failing Fontan circulation, defined as decrease in functional capacity. Secondary Objective(s): - Investigating predictors of decrease in NYHA class of Fontan…
The main objectives are 1) is to evaluate the prevalence of cardiac complications long-term after ASO by investigation of cardiac function as well as clinical outcome and to determine which factors (associated with life style or operative techniques…
To investigate whether the incidence of major thromboembolic complications is reduced with On-X compared to St. Jude medical.
The main goal of this study is to investigate the performance of two CGM devices, FreeStyle Navigator® CGM system and Guardian® RT in relation to the subcutaneous microcirculatory perfusion (as measured by the orthogonal polarization spectral…
The purpose of this audit is to demonstrate the long-term patency of Corlink device compared to the standard "coronary artery bypass grafting (CABG). We also offer this to patients in the study population an extra quality
Four weeks after discharge what are the effects of telemonitoring with patients after cardiac surgery on: 1. Quality of life (SF-36)2. The number of readmissions within four weeks3. The number of relevant complications:atrial fibrillationrelapse…
To evaluate and compare complication and mortality rates tocurrent rates available for repairs with commercially availableannuloplasty rings. (0, 0+)
To get insight in the long term results (mortality, morbidity and cardiologic function) of patients with congenital heart disease operated at young age. To compare whether the changes in surgical techniques have resulted in an increase of (…
The purpose of this study is to demonstrate equivalency of the Cardica * C - Port Xa anastomosis compared to hand sutured anastomoses in patients undergoing CABG with respect to 12 months patency at distal anastomosis site.