133 results
To quantify the role of different abnormal loading conditions on atrial and ventricular electropathology in paediatric patients with CHD.
To test the effect and incidence of hypoxemia when oxygen supplementation through HFNC as compared to LFNC in patients with atrial fibrillation undergoing point-by-point ablation (like RFCA or Galaxy PFA) and deep sedation.
To identify predictors of success of AF ablation including clinical factors, AF recurrence patterns, anatomical and electrophysiological characteristics, circulating biomarkers and individual genetic background.
The primary objective of this study is to describe and to quantify the change in cardiac mechanoenergetics, expressed by PVL monitoring (reflected by the parameters stroke work, potential energy and pressure-volume area), in patients undergoing…
The first aim of this study is to use an in vitro approach using patient*s derived material to accurately and rapidly predict the optimal therapeutic approach that will predict a good clinical response in individual patients. The second aim of this…
The primary objective of this study is to provide a supportive model for optimal coagulation management in the OR and/or ICU to reduce blood loss. This support will be divided into two models to first assess a problem in the coagulation cascade and…
The objective of this study is to evaluate the reliability of the Ablacon Electrographic Flow (EGF) algorithm technology (Ablamap® Software) to identify AF sources and guide ablation therapy in patients with persistent atrial fibrillation.
Prevention of diminished hand sensibility (and secondary: hand function) after trans radial access coronary angiography by shorter wrist compression time using Statseal hemostasis.
Proof of Principle: to assess feasibility to measure; (1) a reproducible 1st thermal IDC, (2) at least 1 recirculation IDC using the FBG photonic sensor both peripheral and nasal. - to compare the acquired Stroke Volume (SV) and Cardiac Output (CO)…
The primary objective of this acute feasibility study is to assess the defibrillation threshold (DFT) when adding a second left parasternal electrode to an S-ICD system.The secondary objective is to assess the efficacy of the 2-electrode…
The primary objective of this study is to study the effects of intraoperative dexamethasone administration on postoperative recovery following cardiac surgery.
The aim of this randomized trial is to appraise the impact of IABP in the treatment of early stages of cardiogenic shock, irrespective of etiology. Findings of this randomized trial may enhance clinical decision making regarding the use of MCS in…
The INVA-SOUND-MRI (INVAsive, ultraSOUND and MRI assessment of transvalvular gradients after transcatheter aortic valve implantation) study aims to elucidate: 1) The accuracy of transaortic gradient assessment with different modalities (invasive,…
The objective of the ADVANTAGE AF Study is to establish the safety and effectiveness of the FARAPULSE Pulsed Field Ablation System (FARAPULSE PFA System) for treatment of drug resistant, symptomatic persistent atrial fibrillation (PersAF).
Primary: - To determine the pharmacokinetics and pharmacodynamics of morphine, oxycodone and its metabolites in frail elderly undergoing cardiac surgery. Secondary: - To assess the influence of covariates such as frailty, serum creatinine,…
The primary objective of the study is survival on a Carmat device at 180 days post-implant* or survival to cardiac transplantation if occurring before 180 days post-implant**. * The beginning of the implant procedure is defined as the start of the…
To compare efficacy and cost-effectiveness of early AF ablation by PVI using cryoballoon therapy with standard (medicinal) therapy in patients with heart failure with reduced ejection fraction.
To demonstrate the added value of TCD emboli detection in patients after cardiac surgery. To investigate the possibility of an early detection of silent cerebral embolization after a cardiac surgery procedure to identify a subset of patients with an…
The aim of this study is to compare health status, quality of life outcomes and subjective postoperative pain for patients with severe aortic stenosis treated either with a limited access aortic valve replacement or with a conventional aortic valve…
Primary Objective:The study aims to assess freedom from AF ten years after the procedure without the use of antiarrhythmic drugs in patients who underwent thoracoscopic ablation in advanced AF with or without GP ablation. Secondary Objectives:1. To…