133 results
Primary Objective:Our overall aim is to develop an easy-to-use, and interpretive method for the early detection of valvular heart disease and thoracic aortic aneurysm based on arterial blood pressure waveforms, collected non-invasively. Therefore,…
Purpose of this prospective, randomized, controlled, multi-center study is to evaluate the safety and efficacy of Transcatheter Aortic Valve Implantation (TAVI) as compared to surgical aortic valve replacement (SAVR) in female patients with severe…
To demonstrate the safety, performance and effectiveness of the EMPOWER* Modular Pacing System (MPS), as well as the EMPOWER and EMBLEM* Subcutaneous ICD Coordinated System. Additionally, data from this study may be used to support pre-market and…
To describe the perioperative biomarker response in surgical patients with and without a postoperative complication.To construct a preoperative and postoperative prediction model for postoperative complications to improve risk stratification and…
Determine the difference in mitoPO2 in between the cannulated and non-cannulated and the difference in DLS red blood cell velocity (RBV) between the two legs, in patients undergoing a cardiopulmonary bypass (CPB) MICS with standard cannulation.
The primary objective of this study is to assess the effects of CPPF, executed by Haermonics Flush, in comparison with standard care on clinically relevant endpoints, like re-explorations, in a population of cardiac surgery patients that have an…
In this study, we aim to investigate the postoperative time course of microcirculatory parameters in patients admitted to the ICU after cardiothoracic surgery with and without circulatory shock. Secondary objectives:* To study the postoperative time…
to quantify atrial electropathology of the endocardium in adult patients with CHD and to correlate clinical characteristics, atrial volume, electropathology, atrial ectopy and features of pre- and post-procedural atrial fibrillation.
The primary objective of this study is to assess wall shear stress in the left ventricle outflow tract using 4D flow CMR in healthy controls, asymptomatic HCM and before and after surgical myectomy in patients with HOCM,
To test whether valve surgery plus medical therapy is superior to medical therapy alone for treatment of endocarditis.
We aim to study the patient specific threshold for arterial blood pressure to maintain adequate cerebral perfusion (CBFV) in the perioperative setting and the association between perioperative abnormalities with postoperative brain damage and…
to demonstrate persistent atrial fibrillation is associated with endocardial and epicardial dissociation of the heart.
To elucidate the correlation between proteostasis marker levels in serum and atrial tissue, and initiation and progression of AF in patients.
To create a clinical characterization platform for patients scheduled for AF ablations with the purpose to optimize health care processes for patients with atrial fibrillation and related translational research. Continuous data collection and…
The primary objective of the study is to assess the safety and efficacy of a pressure microcatheter guided treatment decision and PCI optimization compared to a pressure wire based strategy.
The primary objective of this study is to investigate if a smart technology intervention could improve prognostic factors in patients who underwent cardiovascular surgery, more specifically earlier identification of adverse events such as sternal…
The primary study objective is the assessment of changes in the stress exhibited by patients using the SAM solution versus those in the control group until the surgical procedure.
Primary objective: Is there a difference in the change in perfused vessel density between obese and lean subjects after cardiac surgery with cardiopulmonary bypass?Secondary Objectives * Is there a difference in baseline perfused vessel density…
The study objective is to compare the safety and efficacy of repeated catheter ablation within 6 months versus a hybrid procedure consisting of endoscopic epicardial surgery combined with endocardial catheter ablation (performed one-stage) in…
To determine the safety, feasibility and efficacy of targeted left ventricular lead placement with CRT procedures, using the CARTBox software.