57 results
1. To get new insights in the pathophysiology of PPS by comparing tissue characteristics (histology) of the pericardium in patients with and without PPS. 2. To identify biomarkers that are associated with PPS by collecting 4 blood- and 1 pericardial…
The primary objective is to investigate the determinants of aortic root deformation occurring >= 3 months after successful ASO implantation in adult patients with an atrial septal defect.
The primary objective of this study is to identify in what manner micro- and macro hemodynamic parameters responds to critical illness and therapy, and to determine how this interaction is related to different states of organ dysfunction (heart,…
Ex vivo study: What is the relation between increasing heparin concentrations and different protamine:heparin-ratio*s with POC-PT values in blood drawn from healthy volunteers?Clinical study in cardiac surgery: Does the POC-PT device correspond with…
To investigate whether high resolution multi-site epicardial mapping of the atria in patients with structural heart disease undergoing cardiac surgery can identify patients at risk for developing early post-operative atrial fibrillation. The…
- To determine the effects of the pacing site on prevention of AF episodes - To examine the relation between the pacing site, reduction of AF episodes, quality of life, heart failure, number of cardioversions, frequency and duration of hospital…
The aim of this project is to elucidate how corticosteroids protect cardiac surgical patients from PNAF. We will therefore examine the modulating effect of prophylactic high-dose corticosteroid administration on perioperative risk factors for PNAF.…
In a randomized controlled trial, the effects of DHCA and ACP during complex neonatal cardiac surgery on organ function and injury will be compared, especially focusing on cerebral damage and neurological outcome. The primary research question is…
1. To compare the induction of a procoagulant state between patients undergoing PVI using the PVAC catheter, the cryoballoon catheter or the cooled tip catheter.2. To compare the incidence of CE on diffusion weighted MRI between the three groups of…
The aim of this clinical study is to investigate whether RIPC induced cardioprotection is associated with an increased amount of mitochondrial HK (mtHK) in the heart.
The goal of this study is to determine if off-pump CABG surgery is associated with better cerebral tissue oxygenation when compared with on-pump CABG. In addition, we would like to compare the results of two different monitors of brain tissue…
Fontan circulation: Analysis of its Impact on quality of life and Rate of deterioration (FAIR study)
Primary Objective: - Investigating the rate of the attrition and predictors of the failing Fontan circulation, defined as decrease in functional capacity. Secondary Objective(s): - Investigating predictors of decrease in NYHA class of Fontan…
To identify the influence of two different biocompatible-coated extracorporeal circuits on the perfused boundary region of the sublingual microvasculature as measured by the GlycoCheck Sidestream Darkfield Imaging camera.
The main objectives are 1) is to evaluate the prevalence of cardiac complications long-term after ASO by investigation of cardiac function as well as clinical outcome and to determine which factors (associated with life style or operative techniques…
The main goal of this study is to investigate the performance of two CGM devices, FreeStyle Navigator® CGM system and Guardian® RT in relation to the subcutaneous microcirculatory perfusion (as measured by the orthogonal polarization spectral…
The primary objective of this study is to evaluate the diagnostic accuracy of coronary artery luminal stenosis and corresponding myocardium perfusion defects in patients with suspected coronary artery disease by use of volume computed tomography..…
We hypothesize that also in patients with diminished left ventricular ejection fraction or left ventricular hypertrophy, echocardiographic Doppler measurement of mitral inflow and venous pulmonary flow more reliably reflects actual left atrial…
The analysis is performed of thrombocyte function before, during and and after CABG surgery with dedicated tests as Light Transmission Aggregometry(LTA), thromboelastography (TEG), Multiple Electrode Aggregrometry (MEA) en Platelet Function Analyzer…
To investigate the relation between characteristics of valve prosthesis on functional outcome andquality of life in adult patients with CHD. To investigate the prevalence and predictors of PPM in a population withCHD. To investigate the incidence of…
In this study we want to evaluate the clinical and diagnostic ability of the micro TEE transducer (7.5 - 5.5 mm diameter tip, 18.5 mm length tip with a 5.2 mm diameter shaft) (Figure 1,2), the smallest multiplane TEE in the world, in pediatric…