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Does a decision aid improve decision making in prosthetic heart valve selection?

Conduct a multicenter randomized clinical trial to assess whether the use of the decision aid results in optimization of shared-decision making and improved quality of life in patients who have been accepted for aortic and/or mitral valve…

Long term effects of congenital heart surgery. Cardiologic and Psychologic results. (LUCCA)

To get insight in the long term results (mortality, morbidity and cardiologic function) of patients with congenital heart disease operated at young age. To compare whether the changes in surgical techniques have resulted in an increase of (…

Microcirculatory changes during cardiac surgery: The effects of different modalities of cardiopulmonary bypass

Does CPB affect microcirculatory function by comparing on-pump (CON-CPB) and off-pump (OFF-PUMP) cardiothoracic surgery?Does pulsatile flow during cardiopulmonary bypass (PULSE-CPB) improve microcirculatory function as compared to continuous flow (…

Evaluation of an electronic device to objectively monitor energy expenditure, physical activity, unrest and autonomic nervous system function in patients admitted to the Intensive Care

The objective of the study is to explore the performance of the Sensewear device during various levels of activation of the autonomic nervous system and sedation in a population patients admitted to an ICU.

Weanen ASV versus Pressure Support

to compare the difference in weaning by ASV and PC/PS

Effect of Clopidogrel (Plavix) on Postoperative Bleeding in Patients undergoing Coronary Artery Bypass Surgery. A prospective randomized controlled study.

To investigate if the interruption of the clopidogrel is necessary before CABG in order to prevent bleeding and other complications, and if so, which is the safe time interval to proceed with surgery. To asses the predictive value of the TEG clot…

POStoperative INTELLiVENT-adaptive support VEntilation in cardiac surgery patients II (POSITiVE II) - a randomized clinical trial

The here proposed randomized clinical trial, named *POStoperative INTELLiVENT-adaptive support VEntilation in cardiac surgery patients II* (POSITiVE II), compares INTELLiVENT-ASV with conventional ventilation in patients planned for elective cardiac…

The CRYSTAL study: CMR of intraventricular flow analysis and genetic phenotyping in Hypertrophic Cardiomyopathy (HCM): a roadmap for surgical myectomy

The primary objective of this study is to assess wall shear stress in the left ventricle outflow tract using 4D flow CMR in healthy controls, asymptomatic HCM and before and after surgical myectomy in patients with HOCM,

Empowering patients by professional STress Avoidance and Recovery Services using the Stress Adaptative Manager (SAM) solution

The primary study objective is the assessment of changes in the stress exhibited by patients using the SAM solution versus those in the control group until the surgical procedure.

Pilot study: A comparison of the extent of haemolysis induced by conventional versus miniaturised extracorporeal circulation during coronary artery bypass grafting surgery, and the influence on the release of damage associated molecular patterns (DAMPs), leukocyte activation and neutrophil extracellular trap (NET) formation.

Primary Objective: To compare the extent of haemolysis associated with the use of the conventional versus the miniaturised heart lung machine in the Amphia hospital, with the aim to set up evidence-based guidelines for the use of a specific type of…