31 results
1) Evaluating the effect and recovery of glioma surgery in eloquent areas on cognitive functioning.2) Examining the effec tof glioma surgery in eloquent areas on quality of life.3) Examining the effect of gliomas in eloquent areas on the…
To evaluate the efficacy and cost-effectiveness of CBCT imaging compared to panoramic radiography prior to removal of third molars in reducing patient*s morbidity.
1. Identification of gene(s) causing RS. 2. Understanding of the molecular and cellular mechanisms leading to the various manifestations of RS.3. Enabling molecular diagnostics for RS.
The aim of this prospective study is the prevention of progression of premalignant lesions to invasive head and neck cancer by modifying the out-patient follow up and patient management.
Primary objectives:(1) Prevent progression of precursor lesions of the head and neck mucosa by treating selected lesions at risk for malignant outgrowth(2) Demonstrate that the detection of chromosomal instability (CIN) is indeed a powerful tool to…
The objective of this study is to assess whether or not apical surgery that is carried out with the help of a microscope has a higher success rate than apical surgery without the use of a microscope. No RCT is found in present literature (Del Fabbro…
Primary Objective: What are the consequences of irradiation for the human jaw bone and oral mucosa on a macroscopic, microscopic and molecular level?Can possible prognostic factors be identified for the occurrence of peri-implantitis, dental implant…
To evaluate the feasibility and potential of sentinel node biopsy in patients with (recurrences of) laryngeal carcinomas and clinically negative neck undergoing total laryngectomy and neck dissection.
Aim of studyTo investigate whether patients with disease eligible for (salvage) surgery would potentially benefit from immunotherapy, we want to study the anti-tumor reactivity of T cells that have infiltrated the tumor. Infiltration of T cells in…
Primary Objective1. Investigate the feasibility of intraoperative imaging with CBCT in open maxillectomy for verifying resection of the intended treatment volume. 2. Assess the feasibility of the intended treatment volume segmentation and resection…
This study has been transitioned to CTIS with ID 2024-514233-37-00 check the CTIS register for the current data. To evaluate the feasibility and prove the concept of sentinel node biopsy in patients with carcinoma of the parotid gland and scheduled…
(1) to create and train an algorithm to generate synthetic CT images of the craniofacial area(2) to evaluate the resulting synthetic CT images in terms of geometrical accurate visualization of the craniofacial osseous structures compared to the…
The primary objective is to clarify the frequency of t-BPPV in patients after mild TBI. Secondary objectives are: assessment of the symptoms of t-BPPV and the treatment success of t-BPPV.
The primary objective of this study is to assess the diagnostic accuracy, in terms of sensitivity and negative predictive value, of preoperative CT lymphography as compared with conventional lymphoscintigraphy for SLN detection. Secondly, we aim to…
We propose to use an alternative superparamagnetic tracer containing ironoxide, which can be detected with MRI and with a magnetic probe. The spatial resolution of MRI is superior to gamma camera detection. Moreover, there is no radiation exposure…
To investigate the timing and coordination of speech articulation and its relation to speech disorders of people who have been treated for oral cancer with a major resec-tion. This information will lead to a better understanding of articulation and…
With this prospective randomized clinical trial, we aim to investigate if the use of prophylactic PMMF on the pharyngeal closure for reinforcement in TL patients under high risk for PCF because of low (SMM), can reduce the risk of PCF to a level of…
As verbs are better indicators of everyday language ability than nouns, the current project characterizes verb processing and verb learning abilities of children with PPFTs, and compares them to the abilities of typically developing children (aim 1…
This study aims to explore the rate of contralateral lymphatic drainage and occult contralateral metastases in patients with lateralized OSCC, a clinically negative contralateral neck and clinical ipsilateral lymph node metastases metastases or a…
The primary objective of this study is to assess the diagnostic accuracy, in terms of sensitivity and negative predictive value, of preoperative 68Ga-Tilmanocept PET/CT combined with conventional lymphoscintigraphy for SLN detection. Besides, we aim…