72 results
The primary objective of this project is to evaluate the primary and secondary technique effectiveness of IRE for centrally located colorectal liver metastases that are neither amenable for resection nor for other local ablation methods due to the…
The aim of this study is to get insight into the long-term clinical course of HAML*s in order to develop a treatment algorithm. Primary Objective: The main study parameters are recurrence, growth or development of new HAML tumors.
To determine safety and technical feasibility of stereotactic radiotherapy for locally advanced and locally recurrent pancreatic carcinoma.
The primary objective of this study is to evaluate the safety in terms of complication rate of IRE in the treatment of colorectal liver metastasis/es <3,5 cm in patients undergoing surgical resection (metastatectomy, segmental liver resection…
Main objectiveTo investigate feasibility and safety of tumor ablation using IRE in patients with irresectable locally advanced pancreatic head carcinomas.Secondary objective(s)To investigate tumor downstaging efficacy, pain perception and hospital…
To demonstrate that primary LC as compared to PC is preferable with respect to morbidity and mortality in high risk surgical patients (APACHE-II score 7-14) with acute calculous cholecystitis.
The ORANGE-II trial is a randomised controlled trial that will provide evidence on the merits of laparoscopic surgery in patients undergoing a left lateral hepatic sectionectomy and participating in an enhanced recovery programme.
To assess if preoxygenation with 100% O2 or preoxygenation with 100% O2 and PEEP are different with respect to the development of atelectasis as determined by lung computed tomography.
This trial will be a first-in-man study. It should therefore demonstrate the feasibility and accuracy of liver tumor ablation. Since image-guided tumor ablation techniques, such as MR-HIFU, leave the coagulated tumor in situ, treatment accuracy is…
1. To characterize the efficacy of topical Fibrocaps plus gelatin sponge, as compared to gelatin sponge alone, in surgical subjects when control of mild to moderate bleeding by standard surgical techniques is ineffective and/or impractical2. To…
To assess whether radiofrequency ablation in the liver is associated with hypoxia in the rim of the induced necrosis.
For further details see - Protocol section: 2 - Aimo Assessment of the accuracy of the FCH PET/CT scan in diagnosing HCC. o Assesment of radical surgical resection, using the FCH PET/CTscan.o Assesment of recurrence after surgical resection, using…
To reduce intraoperative blood loss and enhance tolerance of the FRL to I/R injury during right hemihepatectomy under vascular exclusion by means of in situ hypothermic perfusion with retrograde outflow (R-IHP) of the FRL.
The primary objective of this study is to assess whether *omics technologies are sensitive and specific enough to be used as a chemical risk assessment tool for humans. More specifically the study will demonstrate if there are different and / or…
The aim of this study is to determine the clinical benefit of effective antiviral treatment in patients with advanced fibrosis due to chronic hepatitis C infection.
This study aims to increase the knowledge on perioperative cardiovascular function and volume management in liver transplantation in order to provide a more scientifically based approach to cardiovascular and fluid management. This may be beneficial…
The primary objective of this study is to evaluate the ability of PET-MRI to detect LSR during the first year of follow-up after RFA treatment of CRLM as compared with ceCT and PET-CT. Standard reference will be histology (when available) or…
To evaluate safety and efficacy of endobiliary RFA as a treatment for biliary SEMS occlusion caused by tissue ingrowth.
Main objective researchInvestigate whether a significant difference exists in pain (VAS score) between the conventional laparoscopic approach and the approach for a gallbladder removal LESSSecondary goalsa. Explore the possibility of a significant…
The objective of this study is to evaluate the safety and hemostatic effectiveness of FP versus SoCtreatment in controlling parenchymal bleeding during hepatic surgery.