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The use of SPEctroscopy during Endoscopy for Detection of BiLIary Strictures

Primary:- The feasibility of SFR spectroscopy incorporated in an ERCP procedure.Secondary:- Determine physiological differences between benign and malignant biliary strictures, based on the obtained spectra acquired over a broad wavelength range (…

Hepatic arterial infusion pump chemotherapy in patients with unresectable intrahepatic cholangiocarcinoma

The aim of the study is to demonstrate that HAIP chemotherapy is an effective treatment for unresectable intrahepatic cholangiocarcinomas.

COLLISION-XL trial: Unresectable colorectal liver metastases: stereotactic body radiotherapy versus microwave ablation - a phase II prospective randomized controlled trial for CRLM 3-5 cm

The primary objective is to compare efficacy of MWA to the efficacy of SBRT with regards to the primary endpoint (local tumour progression free survival at 1 year [1-year LTPFS]) in patients with unresectable CRLM (3 - 5 cm) that are unsuitable for…

Intraprocedural assessment of Ablation Margins using COMPuted tomography co-registration in primary LivEr Tumor treatment with percutanEous ablation: IAMCOMPLETE primary

To investigate the feasibility of co-registration with MIRADA XD of pre- and post-ablation CT using an optimized scanning protocol. Secondary objectives will be to investigate the reproducibility of CT-CT co-registration, to determine the duration…

Combining drug-eluting bead transarterial chemoembolisation and radioembolization for treatment of colorectal liver metastases: DEBIR90Y study

This study has been transitioned to CTIS with ID 2024-514767-26-00 check the CTIS register for the current data. To find the maximum tolerated dose of glass yttrium-90 (90Y) microspheres (TheraSphere®), when combined with DEBIRI in patients with…

Perioperative Hepatic Blood Flow in relation to Hepatic Regeneration and Function following major Liver Surgery

Aim of thus study is to observe and correlate the course of hepatic blood flow, liver function and liver regeneration after high risk liver surgery.Furthermore we aim to identify ultrasound, liver function and routine hemodynamic parameters…

Ablation zone delineation with MRI during thermal ablation of liver tumours

To assess the feasibility of real-time MRI temperature monitoring and ablation zone assessment during thermal ablation of liver tumours.