371 results
To determine the safety, feasibility, and tolerability of adding PIPAC with oxaliplatin (92 mg/m2) to systemic chemotherapy in patients with isolated PM from CRC.
Primary objective is to gain insight into risk acceptation of serious adverse events (<30 days) in bariatric surgery. Secondary objectives are the expected weight loss, risk acceptation of mortality, risk acceptation of serious adverse events…
Primary Objective:Feasibility and safety of an in-house developed electromagnetic navigation system during abdominal surgery.Secondary Objectives: Evaluation of the accuracy of the system. Evaluation of possible improvements of the navigation…
Physical ExeRcise Following Esophageal Cancer Treatment (PERFECT) Study: a randomized clinical trial
Primary Objective: - To investigate whether a 12-week exercise intervention increases HRQoL in patients after curatively intended EC surgery compared to a usual care control group.Secondary Objective(s): - To investigate whether a 12-week exercise…
To determine whether UGI series is a feasible technique for 2D and 3D gastric pouch and gastroenterostomy size measurements after Roux-en-Y gastric bypass surgery.
To define the optimum laparoscopic hiatus hernia repair, ensuring long-term effect with minimal postoperative side effects.
Primary objective: to objectify the influence of Roux-en-y gastric bypass surgery on the prevalence of lactose intolerance / malabsorption.Secondary objective: To determine the usability of the lactose hydrogen breath test, the lactose tolerance…
This trial aims to investigate if peroperative administration of TA can reduce the peroperative and postoperative hemorrhage rates in laparoscopic sleeve gastrectomy.
The primary objective is to evaluate the EndoRotor®*s ability to safely remove non-viable/necrotic tissue for direct endoscopic necrosectomy in patients with walled off pancreatic necrosis
Primary Objective: To evaluate the effects of LRYGB with subtotal gastrectomy (LRYGB+) as compared to standard LRYGB (LRYGB-) on striatal D2/D3 receptor availability and dopamine release as well as on whole brain serotonergic activity. Secondary…
This study has been transitioned to CTIS with ID 2023-509360-24-00 check the CTIS register for the current data. Primary objectives: This study has co-primary objectives:• To compare OS of nivolumab versus placebo in subjects with resected EC or GEJ…
In attempt to improve the quality of the TME procedure in low rectal cancer and further improve morbidity the TaTME has been developed, in which the rectum is dissected transanally according to TME principles. First series have been described since…
This study has been transitioned to CTIS with ID 2024-517410-15-01 check the CTIS register for the current data. The aim of this study is to determine the oncological safety, treatment related morbidity, and the functional outcome of local excision…
To test the first feasibility and safety of intratumoral 166-holmium microspheres implantation in pancreatic cancer in a controlled, open-surgery setting.
To assess the predictive value of immune monitoring after colorectal surgery for early detection of postoperative infectious complications.
Evaluate the feasibility of an investigational lead to be temporarily applied to and removed from the splenic neurovascular bunble (NVB)
The objective of this study is to confirm procedural performance of the Exalt single-use duodenoscope in Endoscopic Retrograde Cholangiopancreatography (ERCP) or other duodenoscope-based procedures.
Primary objective:To demonstrate that Eziclen, given on the day before colonoscopy has non-inferior efficacy to Klean-Prep on colon cleansing in adolescents aged 12 to 17 years (inclusive) with a body weight > 40 kg, scheduled to undergo a…
To assess the effect of a Roux-en-Y gastric bypass on the pharmacokinetics of a single oral dose of 1000 mg paracetamol
To explore the effects of HBOT on immunologic parameters and oxidative stress.