371 results
The OMEGA trial will primarily investigate if omentum preservation (partial omentectomy) during gastrectomy for gastric cancer is non-inferior to complete omentectomy in terms of three-year overall survival.
Primary Objective: To further develop and evaluate a personalised patient-centred surveillance programme including a feedback platform for patients after curative treatment for CRC in terms of health-related quality of life (HRQoL).The goal is for…
Evaluation of IORT accuracy and effectiveness during rectal cancer surgery by determining the exact position and direction of the IORT beam through the use of an intra-operative electromagnetic image-guided navigation system.
The aim of the PELICAN trial is to investigate the survival benefit of RFA followed by chemotherapy as compared to standard palliative chemotherapy alone in patients with LAPC.
We aim to confirm that Maastro endoluminal HDR contact brachytherapy boosting is feasible and may increase the chance of functional organ sparing of the rectum in patients with rectal cancer.
The aim of the study is to investigate whether SI-NETs can be visualized with indocyanine green (ICG) and near-infrared (NIR) fluorescence imaging (FLI).
To compare L-MILP with R-MILP for benign and pre-malignant lesions of the pancreas in high-volume centers, regarding:1. Peri- and postoperative outcomes in terms of COMPOS-panc left score, for non-inferiority2. Total hospital-related costs, for…
The purpose of this research is to explore the needs of obesity patients and their partners or loved ones, to permanently change their lifestyle. These knowledge and insights can be used for new developments or to improve existing products/…
To compare MIDP with ODP regarding radical resection rate) for pancreatic ductal adenocarcinoma (PDAC) in the pancreatic body or tail.
In this prospective, double-blind, randomized controlled trial, we investigate the hypothesis that regional anesthesia provided by WCI with ropivacaine will reduce pain postoperatively (as measured with COMFORT behavior scale and Numeric Rating…
The main objective of this study is to evaluate whether earlier establishment of Critical View of Safety can be obtained during laparoscopic cholecystectomy, by applying NIRF laparoscopic imaging as an adjunct to conventional laparoscopic imaging…
1. To assess safety of different doses of a single iv injection of SGM-1012. To assess the performance of SGM-101 in the intraoperative detection of colorectal or pancreas cancer by:a. Tumor-to-background ratio (TBR);b. Concordance between…
Primary ObjectivesTo assess the efficacy of 0.13mg/kg EMI-137 IV injection to detect lesions during colonoscopy, in subjects at high suspicion of developing colorectal cancer by:- Comparing the number of pathological lesions detected with WL with…
To determine the effect of Pre-OP, in addition to perioperative intravenous antimicrobial prophylaxis on the cumulative incidence of deep surgical site infections (SSI) and/or mortality within 30 days after surgery in patients undergoing elective…
Primary Objective: To evaluate the effect of PFR compared to standard treatment on FI in patients after LAR, by measuring the Wexner-score and the Fecal Incontinence Quality of Life Score (FIQL-score).Secondary objective:To analyse the cost…
Primary: Feasibility of an in-house developed electromagnetic navigation system during real-time tumour tracking in rectal surgery.Secondary: Evaluation of the accuracy of the system. * Determine the accuracy of the navigation system relative to…
The goal of this pilot study is to calculate the sensitivity and specificity for discriminating tumour and benign tissues in vivo in colorectal cancer patients based on optical spectroscopy measurements. The secondary goal of this study is to…
The ICAN research question is: What is the effectiveness of an intrathoracic compared to a cervical esophagogastric anastomosis after (hybrid) minimally invasive esophagectomy in terms of anastomotic leakage, morbidity, quality of life and costs?
The objective of the study is to investigate whether early ERC plus ES in patients with suspected APB and a predicted severe disease course without cholangitis, lowers the incidence of a composite endpoint of mortality and severe morbidity. Major…
The aim of this study is to determine the cost-effectiveness of pelvic floor reconstruction using a biological mesh afterstandardized eAPR with neo-adjuvant (chemo)radiotherapy.