23 results
To determine which advanced image enhanced modality is the most feasible for the detection of endometriosis lesions, with respect to the specificity and sensitivity of the investigated modalities. To determine which imaging modality reveals more…
Both RCTs and long-term follow-up studies are required to establish optimal fetal management and provide clinicians a better understanding of the impact of these early interventions on child development in order to improve the quality of antenatal…
To determine the clinical effectiveness of adjuvant therapy given to all unstaged (no lymph node dissection) high risk stage 1 endometrial cancer, compared with only node positive (staged) cases as judged by full lymph node dissection.
1. To study the safety and feasibility of para-aortic surgical staging in advanced cervical cancer in the Netherlands.2. To provide insight in the possible effectiveness of para-aortic surgical staging in advanced cervical cancer as compared to…
To test an intra-operative fluorescent camera system with a fluorescent optical agent in detection of the sentinel lymph node. This will be compared to the standard method with radiocolloid and patent blue.
To test a near-infrared fluorescence camerasystem in order to detect folate-FITC in tumour tissue in women with ovarian cancer who undergo cytoreductive surgery.
To test the value of preoperatively performed urodynamics with regard to outcome of surgery for stress urinary incontinence (SUI) and to examine whether not performing urodynamics preoperatively is more cost effective than performing urodynamics…
1. Compare generic and pelvic-floor-specific QOL in patients who have been treated or gynaecologic cancer to that of patients without cancer attending a gynaecologist for pelvic floor symptoms.2. Examine how many and which patients receive or have…
SCAR study
Sonohysterographic evaluation of caesarean scar defects and determination of risk factors
Determination of the incidence of a scar defect .Determination of riskfactors for develpment of scar defects
1. To assess the feasibility of SLN identification in endometrial cancer.2. To examine in how many cases SLN biopsy provides results that will tailor adjuvant treatment3. To investigate if SLN biopsy in women with low- and intermediate-risk…
OBJECTIVE: through MRI research, we want to map the pelvic floor structures that are involved in holding a pessary in place
The primary objective of this study is to develop an diagnostic algorithm using ct-DNA, and TEPs as liquid biomarkers in combination with the existing ultrasound models (RMI and IOTA-models) and biomarkers (CA125 and HE4) to differentiate between…
The objective of this study is to assess the costs and effects of two strategiesof tubaI testing during the fertility work-up, one based on the new technique hysterosalpingo-foam sonography (HyFoSy) (innovative strategy) and the other on…
Primary objective: To identify those groups of pregnant patients, planned to undergo cesarean delivery, who are at risk to develop severe hypotension (defined as a decrease of at least15% from the baseline tension) based on their preoperative volume…
Primary objective:To distinguish benign ovarium lesions from early cancer lesions, based upon their platelet RNA profile. Secondary objectives:* Evaluate the diagnostic accuracy of platelet RNA profiling in detecting early-stage ovarium cancer…
The primary objective is to assess the feasibility of intravenous injection of ICG to detect the border between healthy - and therefore fluorescent - bowel versus endometriosis.
Primary* To confirm the efficacy of OTL38 in combination with fluorescent light to detect additional Folate Receptor-positive (FR+) ovarian cancer lesions not detected by palpation and visualization under normal light in patients with FR+ ovarian…
Primary objective:- To assess the feasibility of a single intravenous injection of OTL38 in detecting endometriosis during surgery by determining the concordance between fluorescent signal and histopathological confirmed endometriotic tissue.- To…
To assess 1) the feasibility of in vivo measurement of biomechanical properties of the vaginal wall with the use of cutometry (Cutometer MPA 580 4mm) and indentometry (Indentometer IDM 800) and 2) the biomechanical properties of the vaginal wall.
To determine the clinical effectiveness of adjuvant therapy given to all unstaged (no lymph node dissection) high risk stage 1 endometrial cancer, compared with only node positive (staged) cases as judged by fulllymph node dissection.