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Patient controlled analgesia i.v. with morphine versus continuous epidural analgesia with bupivacaïne and sufentanil as pain relief after caesarean section.

We would like to research wether there is a difference in time of mobilization between women getting iv PCA with Morphine (PCA)as opposed to women getting continuous epidural analgesia (CEA)with bupivacaine and sufentanil.We expect that the PCA will…

Hysterectomy with TUbectomy (HYSTUB) study

Does salpingectomy during a hysterectomy cause POF? Secundary: what is the incidence of premalignant changes within Fallopian tubes of women without a hereditary high risk to develop serous carcinoma?

Sexual complaints in female cancer survivors: Is there a need for treatment?

Observational multicenter trialThe following research questions (Q) will be addressed in patients (and partners) (Q1) whether sexual problems as reported by female cancer survivors are personally distressing and if so, ( Q2) what are possible…

The role of immunology in diabetes mellitus and pregnancy

Primary Objective: To determine the local and peripheral immune response in diabetic pregnancies in comparison to healthy controls. Immune response will be measured by counting Th1/Th2-cells, Tregs, NK-cells, monocytes and granulocytes. Produced…

Prevalence of overactive bladder (OAB) in patients with pelvic organ prolapse (POP) and predictors of symptoms of OAB after surgical correction of POP.

The primary aim of this research project is to investigate the prevalence and bother of OAB before and after POP repair surgery and to determine changes in bladder function after surgery. Secondary aim is to identify predictors of persistence,…

Paradoxical and venous Gas Embolism During Hysteroscopic Surgery Detected by Trans Esophageal Echocardiography: A comparison using either bipolar or monopolar diathermia

To determine the incidence and grade of venous emboli and/or paradoxical gas emboli during hysteroscopy surgery using TOE. In addition, a comparison will be made using either bipolar or monopolar diathermia. Knowing the incidence and severity of…

An observational controlled study on vaginal blood flow and sexual functioning after early stage cervical cancer treatment

This study will investigate a comparison group of women treated with a conventional (non-nerve sparing) RHL for cervical cancer (CC) at the Academic Medical Centre (AMC). Together with the data collected of women treated with a nerve sparing radical…

SUBSTITUTION OF USUAL PERIOPERATIVE CARE BY E-HEALTH & ICT; a cost-effectiveness analysis

This study proposal hypothesizes that huge health efficiency gains can be achieved by substitution and improvement of usualperi operative care by Ehealth and ICT. The main research question is: Is perioperative E-health & ICT costeffective…

Removal of indwelling urinary catheter after vaginal prolapse surgery; removal on first night versus first morning after surgery.

Primary objective: Does removal of an IUC late at night on the day of vaginal prolapse surgery lead to a decrease in clinical UTIs in the first six weeks after surgery compared to removal on the morning of the first day after surgery?Secondary…