19 results
With the aim to restrict inappropriate FFP transfusions to critically ill patients, a randomized clinical trial will be conducted in a subgoup of ICU patients undergoing an invasive procedure. The objective is to assess the effectiveness and costs…
The primary objective of this study is to investigate whether skeletal muscle glucose metabolism, perioperative glucose control and hemodynamics are affected by increasing physical activity in the weeks preceding surgery in patients identified with…
Time to recurrence of sustained VT and/or appropriate ICD therapy; ATP or shock
In this present study we will assess the effect of a pre-warming intervention before surgery, in order to decrease the temperature gradient from core to periphery and thereby minimize redistribution hypothermia under anesthesia, on (I) the…
In this trial the outcomes of an Ultrapro mesh after endoscopic hernia repair (TEP) will be compared with the outcomes of a heavyweight mesh (Prolene) after TEP hernia repair. The primary objective is to determine the effect of a lightweight mesh (…
Primary Objective:In this pilot study, the authors aim is to investigate whether esketamine reduces the incidence of POD in elderly patientspresenting for noncardiac surgery.Secondary Objective(s):To examine whether esketamine has an effect on the…
The objective of this study is to assess fatigue, physical activity, psychological wellbeing and quality of life in breast cancer patients during and shortly after adjuvant chemotherapy. We will study how often en how intense the symptoms occur. We…
The purpose of this study is to document the efficacy, measured by allogeneic blood transfusion rate, of the Sangvia® Blood Management System when used for intra-operative, and if bleeding continues after surgery, possibly also postoperative…
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The aim of this study is to compare the effect of a postoperativenegative pressure dressing (Prevena (TM) IMS) with a standardwound dressing (care as usual) in clean closed surgical wounds on the prevention of wounddehiscence in low riks and high…
The aim of this study is to compare the effectiveness of a negative pressure dressing (Prevena (TM) IMS) with a standard wound dressing (care as usual) in clean closed surgical wounds on the prevention of wounddehiscence in patients, undergoing an…
to determine whether a pre- and postoperative CR (PRE+POST) program improves the short (up to three months) and long term outcomes (up to one year) after cardiac surgery (i.e. reduction in postoperative surgical complications, readmissions to…
The primary objective is to assess the (preliminary) effectiveness of a 4-week home-based exercise training program on an advanced cycle ergometer and the administration of nutritional supplements on preoperative aerobic capacity as measured by the…
To investigate the effects of disturbing factors during postsurgical hospitalization on participants* wellbeing, in terms of sleep, stress, pain and physical mobility, and how this wellbeing might change during a more personalized hospital stay…
Primary Safety Objective: To describe the safety profile of 20vPnC
Given the above mentioned gaps in knowledge, the aim of this project is to1) Describe the midterm and long-term outcomes of (primary and revision) total hip, total knee and shoulder replacement surgery in terms of health status as a whole, including…
To determine cost-effectiveness of hepatic venous pressure gradient (HVPG)-guided nonselective beta-blocker therapy as compared to standard heart rate-guided beta-blocker therapy in the primary prevention of esophageal variceal bleeding in cirrhotic…
To assess the effect of a bundle of non-pharmacological interventions implemented in the post-anesthesia care unit on the total serum cortisol levels after intermediate and major surgery.
Does the introduction of routine postsurgical anesthesia visits reduce postoperative 30-day mortality?