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A randomized phase III study of neoadjuvant chemotherapy followed by surgery versus surgery alone for patients with High Risk RetroPeritoneal Sarcoma

This study has been transitioned to CTIS with ID 2023-505261-84-00 check the CTIS register for the current data. The primary objective of this study is to assess whether preoperative chemotherapy, as an adjunct to curative-intent surgery, improves…

Towards a minimally invasive approach of atypical lipomatous tumors: the MINIMALIST study

The aim is to develop a minimally invasive approach of both diagnosing and treating ALTs, saving these patients a biopsy, surgery-related complications and morbidities amongst others. As a first step towards a minimally invasive diagnosis, a…

Comparison of clinical and radiographical outcomes following placement of hybrid and moderate rough implants in the posterior mandible of periodontally compromised patients: a 3-year randomized clinical trial

Thel aim of this project is to analyse hybrid implants placed in de posterior mandible of periodontally compromised patients and to compare the treatment outcome of either moderate rough or hybrid implants.

Slowly-resorbable TIGR® Matrix mesh (Novus Scientific, Uppsala Sweden) for totally extraperitoneal (TEP) endoscopic reinforcement of inguinal-related groin pain.

The objective of this study is to collect additional data on the performance and safety of the slowly-resorbable TIGR® mesh in patients undergoing TEP for IGRP. The study endpoints are described below.

Treatment considerations for the surgical therapy of peri-implantitis

The primary objective of this study is to examine clinical and radiographical parameters when executing:- adjuvant antibiotic therapy versus no antibiotic therapy in the resective surgical treatment of 0-, 1- and 2-wall bone defects due to peri-…