58 results
Documentation of the patients' functional recovery and quantification of fusion after implantation of 3-D trabecular titanium cages on the short and long term. These data will be compared with the recently performed randomized CASCADE trial on…
Primary Objective: To assess whether early postoperative AED withdrawal improves cognitive function compared to late withdrawal.Secondary objectives: * To confirm safety of earlier AED withdrawal; we will assess eventual seizure freedom, seizure…
To determine long-term radiological and clinical outcome of a muscle-sparing surgical technique for posterior decompression of the cervical spinal cord (cervical split laminectomy).
Our first goal is collecting high quality raw EEG waves, - measured simultaneously on multiple locations of the brain - during a pharmacological reproducible anesthesia. The goal is to observe EEG patterns that allow the development of technology to…
The objective of this pilot study is to investigate the feasibility of using the Clip system in a human setting in creating an intracranial arteriotomy in a non-occlusive, sutureless fashion. Although the focus is on the technical success of the…
Determination of prognostic value of intraoperative growth hormone levels on postoperative curation for acromegaly in patients undergoing transsphenoidal resection of pituitary adenoma.
A study on extent-related outcome and complications for degenerative cervical spinal disease has not yet been performed. Results of this study may form the basis for a guideline regarding the extent of fixation in degenerative cervical spinal…
The objective of the study is to provide clinical evidence proving that the Aperius* PercLID* System is safe and non-inferior to Standalone Decompressive Surgery (decompressive spinal surgery without additional instrumentation/fixation) with regards…
Primary Objectives:• show effectiveness of the SMSC instrument in 3D correction of the spine prior to placement of the implants.The hypothesis is that to achieve de-rotation of the spine without failure of the pedicle screws, de-rotation has to be…
The first aim is to test the effect of the surgical intervention for fear of blushing in a randomized controlled trail consisting of a robot-assisted highly selective dorsal sympathectomy and a waiting list control group. There are several outcome…
The effect of the intervention on pain an regain of function in de affected extremity. This will be quantified in multiple questionnaires at baseline and three follow-up points, and by clinical evaulation of the hand function at baseline and two…
The primary objective is to avoid cognitive and affective side effects and maintain the beneficial motor effects by selective stimulation of the STN motor part. With the Select Stim project we want to improve the classical operation procedure, in…
The primary endpoint of this feasibility study is the technical success of positioning the SLIDE device to verify the speed and ease of use without unexpected device related adverse events. A technical success is defined that the SLIDE device was…
Does anesthesia itself or transition of anesthesia to an awake state and vice versa lead to changes in the lactate/pyruvate ratio, glucose, glycerol and glutamate concentration as measured in the brain interstitial fluid?Are the metabolic…
To determine if dose-intensifying the adjuvant temozolomide component of the chemoradiation treatment enhances treatment efficacy as measured by overall survival.
To accumulate data from patients who undergo spinal surgery for metastatic cancer, for the purposes of determining the difference in outcome between operations of varying complexity.
Safety and performance will be based on a comparison of overall success rates of the Barricaid ARDand either a concurrent group (nonrandomized) of control patients treated by conventional surgicalmethods (e.g., noninstrumented discectomy) at select…
1. To implant a functional vestibular prosthesis using the ampullar *V*-approach, as developed in our own clinic.2. To investigate protocols for adjusting the vestibular implant (VI) to required settings, regarding:-- Modulation sensitivity--…
Primary objective is to study the number of patients gaining at least 50% pain reduction within 8 weeks following PRF as compared to following a neurectomy. Pain intensity will be measured using numeric pain rating score (NPRS, 0-10) and Verbal…
The purpose of this study is to assess the safety and effectiveness of the Freedom SCS (spinal cord stimulation) System for the treatment of chronic back and leg pain secondary to failed back surgery syndrome (FBSS) over a follow-up period of one…