87 results
The primary endpoint of this feasibility study is the technical success of positioning the SLIDE device to verify the speed and ease of use without unexpected device related adverse events. A technical success is defined that the SLIDE device was…
Does anesthesia itself or transition of anesthesia to an awake state and vice versa lead to changes in the lactate/pyruvate ratio, glucose, glycerol and glutamate concentration as measured in the brain interstitial fluid?Are the metabolic…
To determine if dose-intensifying the adjuvant temozolomide component of the chemoradiation treatment enhances treatment efficacy as measured by overall survival.
Primary objectives of the study are (i) to evaluate short*term safety of HYALOSPINE and (ii) to evaluate efficacy of HYALOSPINE in prevention of adhesions and fibrosis following single* or two*level lumbar laminectomy or laminotomy in patients with…
To determine wether the results of CTR are influenced by postoperative immobilisation of the wrist during nights. Secondly we want to determine wether scar tissue forming is influenced by the technique used to close the wound. (simple vs Donati…
To accumulate data from patients who undergo spinal surgery for metastatic cancer, for the purposes of determining the difference in outcome between operations of varying complexity.
Safety and performance will be based on a comparison of overall success rates of the Barricaid ARDand either a concurrent group (nonrandomized) of control patients treated by conventional surgicalmethods (e.g., noninstrumented discectomy) at select…
The primary objective of the study is to investigate whether the IDD (Intervertebral Differential Dynamics) protocol with Accu-Spina on the VAS low back pain score at 3 months posttreatment.
We hypothesize that ultrasound visualization of the distal sciatic nerve with subsequent ultrasound guided injection of a reduced amount of local anesthetic will result in shorter performance times, equivalent block quality (sensory and motor onset…
Primary outcome parameter is the amount of intra- and postoperative transfusions required. Secondary outcome parameters include intra- and postoperative blood loss, operation time, and postoperative complications and the outcome of…
1. To implant a functional vestibular prosthesis using the ampullar *V*-approach, as developed in our own clinic.2. To investigate protocols for adjusting the vestibular implant (VI) to required settings, regarding:-- Modulation sensitivity--…
Primary objective is to study the number of patients gaining at least 50% pain reduction within 8 weeks following PRF as compared to following a neurectomy. Pain intensity will be measured using numeric pain rating score (NPRS, 0-10) and Verbal…
The purpose of this study is to assess the safety and effectiveness of the Freedom SCS (spinal cord stimulation) System for the treatment of chronic back and leg pain secondary to failed back surgery syndrome (FBSS) over a follow-up period of one…
The primary objective of this study is to characterize the real-world outcomes of high rate spinal cord stimulation (HR-SCS) therapy as an aid in the management of chronic intractable pain of the trunk, including unilateral or bilateral pain…
What is the cost-effectiveness of minimal invasive posterior lumbar interbody fusion in spinal stenosis patients, compared to the standard open fusion?
The primary goal of this study is to compare ultrasound-guided ANB with FHB for analgesia during closed reposition of distal forearm fractures. Secondary goals are evaluation of feasibility in the ED regarding time and procedure success rate.…
To evaluate Multiple Independent Current Control (MICC) perception and sub-perception based programming at Dorsal Column (DC) targets and Dorsal Root (DR) targets for focal foot, knee, or groin pain relief.
To assess the impact of CBT on treatment outcome after lumbar spinal fusion surgery in patients with high pain catastrophizing, a two-center randomized controlled trial comparing CBT care to education.
To compare the (cost-)effectiveness of early surgical hematoma evacuation versus a conservative treatment in elderly patients with a traumatic ASDH.
To document patient outcomes including effectiveness for Boston Scientific Corporation*s VerciseTM CartesiaTM 16-contact Directional Lead (X/HX) with Deep Brain Stimulation (DBS) Systems for the treatment of Parkinson*s Disease (PD).