87 results
In 2013 the Boston Scientific VERCISE System has obtained regulatory approval for use in the European Union, CE mark was granted for the treatment of intractable primary and secondary dystonia.The objective of the study is to compile characteristics…
The aim of the study is to determine the accuracy of pedicle screw placement when using the iNav navigation tool compared with the established computertomography based navigation.
This study will assess the applicability of robotic-assisted microsurgery in DNR after trauma.
To determine if the incidence of adverse local events (local failure or radionecrosis) can be reduced with more than 20% using fSRT versus SRT in one or three fractions.
Research question(s). There are two specific questions to be addressed:1) Is percutaneous transforaminal endoscopic discectomy (PTED) no worse in effectiveness than conventional unilateral open microdiscectomy for patients with symptomatic…
To evaluate the influence of DSA monitoring, provided by the NarcotrendTM monitor, on the speed of emergence and recovery from GA.
To investigate if resection with a margin, that is significantly beyond the radiological contrast enhancement, improves overall survival in selected patients with glioblastoma.
Primary objective: To assess the effect-of initial DXM therapy versus primary surgery on functional outcome (as expressed by the mRS) and costs in patients with a newly diagnosed CSDH respectively after 3 and 12 months.Secondary objectives are:…
This study has been transitioned to CTIS with ID 2024-514927-40-02 check the CTIS register for the current data. To evaluate the efficacy of TXA to prevent surgery for cSDH
Primary: To evaluate whether additional embolization of the middle meningeal artery after surgery for cSDH reduces the recurrent surgery rate. Secondary: to evaluate whether the use of middle meningeal artery embolization after surgical treatment in…
The aim of the proposed study is to examine whether ACDA compared to ACDF is preferable in terms of costs, effectiveness and utility from a hospital and a societal perspective.
In this project we aim to develop a safe and effective technique for ADC/FET-guided resection of IDH-wildtype glioblastoma and grade IV IDH-mutant astrocytoma. The safety concerns neurological deficits and time to start of adjuvant therapy, while…
The primary objective of the proposed research is to investigate in patients with PDD the efficacy of STN-DBS with best oral medical treatment (DBS-group) for disabling motor symptoms during off-drug phase compared to best oral medical treatment…
This study assesses whether EDB surgery will result in a significant reduction in the number of patients without vertigo spells at 12 months follow up, compared to patients who undergo endolymphatic sac decompression.
This study has been transitioned to CTIS with ID 2024-515128-35-00 check the CTIS register for the current data. The primary objective is:• To evaluate the safety and tolerability of a single local i.c. dose of SI-053 to establish the MTD and/or the…
This study has been transitioned to CTIS with ID 2024-514020-16-00 check the CTIS register for the current data. To investigate the effectiveness of s-ketamine as add-on medication to a multimodal pain approach with acetaminophen and opioids…
The primary research question of the trial is to assess whether foot drop, caused by peroneal nerve entrapment in adult patients* recovers better within 9 months after decompressive surgery compared to prolonged standard conservative treatment. *…
Primary Objective: For the primary objective, the following research question is answered: Does performing asleep thalamic DBS provide an equal reduction in tremor compared to awake thalamic DBS, measured by the Essential Tremor Rating Assessment…
This study has been transitioned to CTIS with ID 2024-516338-37-00 check the CTIS register for the current data. This study aims to assess the Pharmacokinetic (PK)-parameters and safety of treatment with BR-003 in humans. BR-003 is a pliable, ring-…
Evaluation of the (cost-)effectiveness of surgical decompression of compressed lower extremity nerves (LEND surgery) compared to patients 'treated' with conventional best care.