12 results
The main object is to evaluate the validity of a diagnostic screening package for bleeding tendency consisting of point-of-care devices when compared with the gold standard for bleeding tendency diagnosis.Other objects which will be investigated are…
The primary objective of this study is to establish the diagnostic accuracy of ultrasound assessment of the synovium in haemophilic arthropathy compared to MRI. Secondary objectives are (2A) to determine whether or not synovial hypertrophy on MRI is…
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Assessing hereditary and aquired determinants of ETP. Evaluating the use of ETP as predictive stand alone test for recurrent DVT and bleeding complications due to anticoagulation therapy in comparisson with the current prediction methods.
Performance is the primary objective of this study and is defined as the ability of the in vitro diagnostic micro-assay to measure von Willebrand factor induced platelet aggregation in accordance with the golden standard diagnostic method, risto-…
1. To evaluate the diagnostic accuracy of a newly developed pediatric BAT.2. To analyze the influence of age, sex and type of bleeding disorder on the total bleeding score and the score of individual bleeding items.
To improve the knowledge and understanding of the (patho)physiology of lymph disorders Main objective: the anatomy of the central lymph vessels, the velocity and direction of lymph flow and its influencers and thoracic duct outlet location and…
The primary objective of this study is to assess the feasibility and safety to image αvβ3-integrin expression in patients with AVM using Ga-68-DOTA-(RGD)2 PET/CT.
To evaluate the diagnostic accuracy of the experimental tests to detect bleeding disorders and to evaluate whether or not they can be used for monitoring the effects of coagulant factor replacement therapy.
Primary objective: to register and investigate Dutch patients suspect for an inherited platelet function disorder, to assess clinical presentation, bleeding score, treatment, burden of disease and quality of life. Secondary objectives: to…
Main objective: - To investigate pyruvate kinase thermal stability in haemoglobinopathies.Secondary objectives: - To investigate the possibility of stimulation of PK activity and thermal stability by use of allosteric activators- To investigate…
The purpose of this study is to identify a pathogenic or likely pathogenic variant in unresolved families with antithrombin deficiency.