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Prevention of local thromboembolic complications during continuous infusion of coagulation factor concentrates: parallel infusion of saline versus heparin and parallel infusion of saline?

To demonstrate that parallel infusion of saline added to the continous infusion of clotting factor concentrates prevents local thromboembolic complications to the same extent as heparin together with a parallel infusion of saline does.

Coronary artery calcification measured with multi detector-row computed tomography in patients with hemophilia A

To investigate whether patients with hemophilia A develop less coronary artery atherosclerosis as compared to non-hemophilic males.

Genotype - phenotype correlation in congenital sideroblastic anemia

The family, described in a publication from 1987, is recently re-identified. It seems to be an asymptomatic condition: there seems to be no anemia or secondary iron overload. Again mapping this family has two purposes:1. Have these patients…