130 results
Our aim is to find the cause of UCH. The subsequent aim is to study the pathogenesis of the entity. The final aim is to find an effective management for the disorder.
Primary Objective: 1: To determine the severity of respiratory problems, treatment modalities and outcome in the first year of life. Secondary Objectives:2a: To evaluate the course of respiratory problems and quality of life on long term follow-up.…
1. Detection of the gene causing Parry-Romberg syndrome. 2. Study of molecular and cellular mechanisms leading to the various manifestations of Parry-Romberg syndrome.
The overall goal of this project is to define and characterize congenital anosmia-related neural plasticity in the human brain and its behavioral consequences. We hypothesize that individuals suffering from congenital anosmia demonstrate wide-spread…
PRIMARY OBJECTIVES- To investigate the PK profile of GLPG2451 administered as two doses of a capsule formulation in healthy subjects.- To assess the safety and tolerability of GLPG2451 administered as two doses of a capsule formulation in healthy…
1: Compare the differences in the PRAGMA-CF score: the volume proportion of the lung with structural airways disease (%Dis), measured from chest CT images at 48 weeks between treatment arms 2: Compare the differences in PRAGMA-CF subscores: the…
Do neonatal critically ill children aged 9-16 years have problems with visuomotor integration? If yes, which aspects of the visuomotor integration are affected and require a possible intervention?
Primary Objective: To validate the predictive value of MRI data for neurocognitive deficits and visual functioning by relating these data from newborns with unisutural craniosynostosis to the psychological and ophthalmologic test results, taken…
We aim to collect blood cells from 40 patients with monogenic epilepsy, with a preference for patients with a pathogenic variant in SCN1A, reprogram these cells into iPSCs and use these iPSCs for differentiation into neurons and neuronal organoids…
Bone-anchored maxillary protraction therapy improves facial profile in cleft children.