54 results
Primary Objectives are to• identify novel (likely) pathogenic genetic variants in familial or young AF patients.• investigate the relation between genetic profiles and electrical (AF) phenotypes.• develop a specific gene panel for AF• construct a…
Primary Objective: To investigate motor developmental outcome at school age of children with CHD compared to typically developing peers.Secondary Objective(s): - To investigate neurodevelopmental outcom eat school age on several developmental…
to quantify atrial electropathology of the endocardium in adult patients with CHD and to correlate clinical characteristics, atrial volume, electropathology, atrial ectopy and features of pre- and post-procedural atrial fibrillation.
The primary objective is to determine whether iRVF patterns and renal damage/function are different in patients with a Fontan circulation compared to age and sex-matched healthy controls.The secondary objectives are to- Identify the prevalence of…
Main objectives of the study can be summarized as follows:1. To thoroughly characterize valve tissue of Barlow*s MR as compared to FED. 2. To investigate the familial distribution of different forms of organic MR and the prevalence of genetic…
The main objective of this study is to assess the prevalence of PFO and RLS in patients with angina and documented coronary artery vasospasm.
The objective of this study is to identify novel genes causing congenital heart disease.
Our main objective is to identify disease modifiers in PLN r14del cardiomyopathy by studying patients are different ends of the PLN r14del cardiomyopathy disease spectrum with respect to differences in the circulating proteome and metabolome and in…
The objective of this study is to identify biomarkers predictive for the development of HCM in asymptomatic MYBPC3 mutation carriers and to identify prognostic biomarkers in mutation carriers in whom the disease has already been revealed. In order…
To visualize and quantify areas of dysfunctional flow in the TCPC and within the single ventricle in patients after a Fontan procedure and try to determine a relationship between these quantitative energetic parameters and adverse outcome.
Primary Objective: Identification of patient characteristics, echocardiographic measurements and biomarkers that can contribute to a better selection of patients that benefit from percutaneous ASD closure at adult age. Secondary Objectives:-…
The primary objective of this study is to describe the intracardiac anatomy and hemodynamics of DILV patients without Fontan circulation using 4D MRI. Furthermore, the functional status and quality of life of these patients will be assessed and…
The main objective of this study is to find biomarkers for the prognosis of the BAV patients by investigating ECFC and EPC functioning, and to gain knowledge on physiological and pathological processes in patients by investigating molecular…
Describe the electrocardiographic changes and areas of late myocardial activation encountered in PLN and PKP2 mutation carriers during ajmaline provocation and the relation of these differences to the development for early stages of arrhythmogenic…