9 results
The objective of this study is to assess potentially new and unique biomarkers that will be specific to patients with HIDS as surrogate outcomes for eventual larger, cohort-controlled clinical studies. Our longitudinal design in a small pilot group…
- The primary research objective is to estimate the prognosis of children affected by ICL. - A secondary research objective is to explore the heredity of ICL between first degree family members.
Using pedigree research in two CVID-families to find clues for genetic testing.
The research strives for a large group of homogeneous AID patients, so that a powerful association study can be performed to detect genetic risk factors. These factors can be shared by several AIZ, or be specific is for a single AID. The aim of this…
Assess correlation between CFH polymorphism and the effect of laser treatment of drusen.
To detect B-cell differentiation and maturation defects in patients with antibody deficiency syndromes of unknown origin (CVID, SAD), which are predictive for clinical complicationsTo detect and sequence candidate genes in subgroups of patients with…
The overall aim of the proposed project is to identify mild PID in elderly patients that distinguish patients with RRTI from individuals with a healthy ageing innate and adaptive immune system. In innate immunity, normal immunosenescence is…
Objective: The primary objective of this study is to investigate the potential of the custom global screening array (GSA) in patients with autoinflammatory disorders. We aim to investigate whether the GSA can pick up genetic variants in genes known…
The primary objective is to identify what causes colchicine resistance in FMF. Additionally, we will try to identify potential interventions to overcome resistance