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B7 Coreceptor Molecules as Clinically-Relevant Surrogate Biomarkers in the Hyper IgD Syndrome (HIDS) form of Mevalonate Kinase Deficiency (MKD)

The objective of this study is to assess potentially new and unique biomarkers that will be specific to patients with HIDS as surrogate outcomes for eventual larger, cohort-controlled clinical studies. Our longitudinal design in a small pilot group…

C1-inhibitor improves efficacy of red blood cell transfusion in patients suffering from autoimmune hemolytic anemia * an open-labeled pilot trial

The aim of the present *proof-of-principle* study is to test in patients suffering from AIHA whether co-administration of C1-inh improves the recovery of RBC transfusion by the inhibition of the activation of the classical pathway of complement. In…