8 results
To investigate the origin of BA we will assess which TLR(s) is/are activated. To test the hypothesis that during development of BA and associated liver fibrosis there is a *leaky gut* and/or a change in microbiome we will use human material to…
A close correlation has been demonstrated between iron absorption and the capacity of gastric juice to release food iron. At high levels of gastric pH (>3,6), negligible amounts of non-haem iron would be released from dietary components and…
To confirm that previous or persisting infection with Chlamydia is associated with the development of perinatal biliary atresia. Furthermore to investigate whether the Chlamydia infection is contracted by vertical transmission from the mothers.
The aim of this study is to investigate the effect of ATP8B1 carrier on hearing in human.
To determine if LA is a familial disease. To identify germline mutations in HNF-1 alpha, ß-catenin and CYP1B1 genes in LA patients. To screen first degree relatives of patients diagnosed with liver adenomatosis for the presence of liver adenomas and…
The aim of this study is to determine whether nose potential difference response is impaired in patients with FIC1-deficiency.
The identification of a new gene(s) that causes autosomal dominant polycystic liver disease.
The primary objective is to evaluate the effect of UDCA and ezetimibe on cholesterol elimination assessed as total faecal sterol concentration. Secondary objective is to assess the effect of UDCA and ezetimibe on plasma lipid profile/composition.