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Long term results of the surgical treatment of bilateral undescended testis with special interest in the fertlity potential.

1. To assess the long term outcome of surgical treatment for bilateral undescended testes with special regard for the fertility potential. 2. In the past 2 different techniques have been used for orchidopexy (with or without involving of the tunica…

Prospective study on the treatment of congenital vaginal agenesis or vaginal hypoplasia - genital reconstruction, gynecological and urological aspects, psychosexual and social aspects and quality of life

Evaluation study on the effectiveness of a new developed vaginal dilatation programme for medical-psychological treatment of vaginal hypoplasia / agenesis.

A randomized, double-blind, controlled phase III study of Stimuvax® (L-BLP25 or BLP25 liposome vaccine) in combination with hormonal treatment versus hormonal treatment alone for first-line therapy of post-menopausal women with estrogen
receptor (ER)-positive and/or progesterone receptor (PgR)-positive, inoperable locally advanced, recurrent, or metastatic breast cancer

PrimaryDemonstration of superior efficacy (as measured by PFS time) of L-BLP25 in combination with hormonal treatment (HT) over placebo plus HT, when used for first-line therapy of hormone receptor-positive (ER+ and/or PgR+), inoperable locally…

Improving risk estimates for familial breast cancer

Main and long-term goal of this project is to gain more knowledge of the relationship between genome-wide genetic variation and the risk of breast cancer, in the context of a positive family history. This knowledge will improve individual risk…

The effect of hormonal replacement therapy on menopausal complaints related to biochemical changes in surgically and naturally postmenopausal women.
A prospective observational comparative study.

The aims of this prospective study are to investigate:1a: Changes in menopausal symptoms and biochemical changes as result of PBSO in premenopausal women.1b: Changes in menopausal symptoms and biochemical changes as result of PBSO in postmenopausal…

Diffusion weighted MRI for evaluation of endometrium and uterine cavity - which phase of the menstrual cycle is optimal for diffusion weighted MR imaging?

In order for DW-MRI to become a possible alternative to invasive diagnostics, we must first optimise the point in the menstrual cycle at which DW-MRI is conducted. This study aims to find the preferable point in the cycle.

Pedicled Peritoneum Vaginoplasty in feminizing genital Surgery; implementation according to IDEAL framework

Primary Objective: To assess the safety of the single flap peritoneum vaginoplasty procedure by studying adverse events and complications during, directly after and within 90 days of the operation. Secondary Objectives: - To assess short- (12 weeks…