27 results
Main objective: To test the efficacy of thyroxine replacement for subclinical hypothyroidism (SCH) in older adults. Primary Objective: To determine multi-modal effects (quality of life; cognitive; musculoskeletal and cardiovascular) of levo-…
Firstly, to study the reduction in sick-leave time achieved by the treatment protocol. Secondly to study the quality of life in the patients treated in the fast-track protocol, to study the reduction in societal costs and to stdy the efficacy of a…
1) To study the late effects of 131-I treatment and TSH suppressive therapy as well as quality of life in patients with childhood-onset DTC. 2) To determine the presence of RET/PTC 1 and 3 translocations and BRAF mutations, and to investigate their…
First objective: To assess improvement in live birth rate after levothyroxine supplementation. Secondary objective: 1) to test the hypothesis that levothyroxine lowers the risk for miscarriage and preterm birth 2) to test the hypothesis that…
Evaluation of the effect of single oral doses of lorazepam on plasma concentration of prolactin
The study aims to determine the value of combined 124I PET and FDG PET to avoid futile treatment with 131I. Secundary aims are to validate functional imaging with histopathological correlation, and to optimize and standardize the new 124I technique…
1. Are there differences between patients and controls in circadian movement rhythmicity and sleep duration?2. Are these objective measures associated with subjective sleep complaints?3. Are these objective measures associated with decreased quality…
Purpose:The main focus of our study is the development, implementation and evaluation of a self-management intervention for patients treated for pituitary adenomas and patients with endocrine diseases in general.
The primary objective of this study is to assess the relation between the short term metabolic changes after start of rhGH therapy and the long term change in height SDS after one and two years of treatment. Secondly, we want to assess the effects…
ObjectiveThe main goal of this investigation is to evaluate the thyroid hormone response in patients with TMNG and control subjects in response to various pharmacological and physiological stimuli, administered according to the dynamic exposure test…
Primary objective:to identify new and improved disease biomarkers and establish the biochemical and molecular basis for variations in the clinical presentation of the different groups of tumors.Secondary objectives:• compare the diagnostic utility…
The purpose of the study is to determine the sensitivity of dopamine platelets levels in patients with clinically suspected or diagnosed HNPGL, abdominal PGL, and pheochromocytoma. Primary Objective: The sensitivity of dopamine levels in platelets…
The main objective of the study is to evaluate differences in body size, body composition and metabolic health at 7 years between children fed postdischarge formula and term formula. Secondary objectives are differences in bone mineralization and…
The primary objective of this study is to assess the effect of individualizing the growth hormone dose versus standard treatment with 1 mg/m2/day on adult height and the first and five year growth response. Secondly, we want to assess the long term…
Evaluating the efficacy and safety of sunitinib in patients with progressive, advanced/metastatic well-differentiated, unresectable pancreatic neuroendocrine tumors.
Primary objective: to obtain an comparison of the diagnostic result after an ultrasound assisted fine needle aspiration cytology (FNAC) of the thyroidal gland by use of a smaller diameter (25G) and / or a special coating.
To describe the differences in macrophage infiltration and mRNA expression of adipocytokines in subcutaneous, omental and perirenal fat tissue in Cushing's syndrome compared to healthy controls.
To identify some of the mechanisms in patients in remission of Cushing*s syndrome that contribute to the persistence of visceral obesity, systemic inflammation, insulin resistance, sarcopenia, a low muscle oxidative capacity and increased risk of…
We aim to investigate thirst in the above mentioned patient groups, applying a Visual Analogue Scale (VAS) and, where ethically acceptable, a new thirst provocation test which we will develop in a group of healthy probands. Using these tools, we aim…
The primary objective of this study is to assess the objective response rates (ORR) for two starting doses of vandetanib, 150 mg and 300 mg in patients with unresectable locally advanced or metastatic MTC having progressive or symptomatic disease.…