16 results
To demonstrate differences in intracutaneous sodium storage between a control population, patients admitted after elective cardiothoracic surgery and septic patients.
To describe the treatment expectations of patients with a pituitary tumor undergoing treatment as well as patients' evaluation of the perioperative trajectory. Moreover, we will determine the fulfilment of expectations and clinical outcomes…
To assess the physiological effects of metformin and hypocaloric dieting on thyroid iodide uptake and thyroid function in healthy volunteers.
To assess the short-term efficacy of stellate ganglion block on hot flush reduction versus sham procedure
* To assess maintenance of biochemical control of octreotide capsules compared to parenteral SRLs in patients with acromegaly, who previouslydemonstrated biochemical control on both treatments.* To assess symptomatic response to octreotide capsules…
Objective: The purpose of this study is to compare the diagnostic surgical rate of a matched control group, derived from a retrospective review of patients without GEC testing, with a prospective GEC tested group.
We aim to further study the characteristics of joint disease in acromegaly and its progression, in order to improve care for this patient group and to get insight into the pathogenesis of osteophytes and cartilage hypertrophy in acromegaly and in…
The aim of this study is to assess whether withdrawing GH treatment after mid-puberty in adolescents with idiopathic isolated GH deficiency, who showed a normal result in a GH stimulation test at retesting, is as effective as continuing GH until…
to assess general sexual functioning, genital sexual responsiveness, subjective sexual responsiveness and affect in women with PCOS , and to make a comparison of these results with the results of an age matched healthy control group of women.…
Primary questionAre changes in vigilance in type 1 and 2 narcolepsy, idiopathic hypersomnia and epilepsy with only nocturnal seizures reflected in differences in the responsiveness of the pupils to light as measured by pupillometry (PIPR) versus…
Our main objective is to assess the difference in PIPR after a blue-light stimulus between hypopituitarism patients with and without a history of CC. Secondary objectives include differences in subjective and objective sleep quality, sleep-wake…
The primary objective of the study is to assess the safety of CORT125134 in patients with endogenousCushing*s syndrome. The secondary objective of the study is to assess the evidence of reduction incortisol activity following treatment with…
To provide further evidence for the role of long-term epigenetic effects of an extra chromosome 21 on HPT-axis associated genes as an explanation of DS associated thyroid phenotype, in a series of DS individuals in whom data on thyroid functioning…
The main goal of this pilot study is to investigate the feasibility of the identification of the parathyroid glands by means of the present commercially available near infrared fluorescence imaging system during thyroid surgery: is it possible to…
This pilot-study is designed to assess the feasibility and efficacy of a new dietary intervention (Happy Weight Dotsplan) and therefore to learn if it might be effective on a broad scale with the inclusion of a larger cohort nationwide. We will…
To determine the minimal dose of protirelin that is effective and safe to normalize plasma thyroid hormone levels in patients with prolonged critical illness.