36 results
To determine whether the attenuated salivary cortisol response in children with asthma can be explained by the maintenance use of inhaled cortiocosteroids, the chronic inflammatory disease, or the attenuated exercise capacity.
To determine the sensitivity and specificity of salivary metanephrines and in patients with PCC/sPGL.
The aim of this study is to determine novel (bio)markers that show a stronger correlation with signs of over- and under-treatment than the conventional adrenal steroid profile in children with CAH.
Objectives: Part 1) To assess the prevalence of PA in general practice (part 1 of this study);Part 2) To describe differences of cardiorenovascular damage in newly diagnosed hypertensive patients with versus without PA (part 2 of this study);Part 3…
To determine the value of multimodality image registration of cone-beam CT (CBCT) and CT in increasing the success rate of adrenal vein sampling procedure compared to procedures without CBCT guidance.
- assessment of age dependent reference values (ages 20 - 70 yrs) for plasma renin (activity and concentration), serum aldosterone and 24h urinary aldosterone (free and metabolites) during a regular diet and after a 3 day oral salt loading test-…
A core part of the scientific efforts of ENS@T researchers bases on the establishment of a common registry and associated collection of biomaterials. Patients with adrenal tumours prospectively included in the ENS@T registry will be asked to provide…
1. Examen if the outcome of the 1 mg Overnight Dexamethasone suppression test is influenced by the use of oral contraception.2. Examen how many weeks after ceasing the use of orale contraception the 1 mg Overnight Dexamethason suppression test is…
Primary objective:to identify new and improved disease biomarkers and establish the biochemical and molecular basis for variations in the clinical presentation of the different groups of tumors.Secondary objectives:• compare the diagnostic utility…
Comparison of the salivary cortisol response after a standardized exercise test between prepubertal heathy children and children with asthma.
Here we propose to perform a prospective, randomized, multicenter study that compares effectiveness of AVS with effectiveness of CT-scanning for the diagnosis of PA subtype. There is no criterion standard for accuracy of the diagnosis of PA-subtype…
The objectives of this pilot study are to explore differences in sleep and fatigue, and the relation with the function of the HPA axis, between survivors of childhood ALL and healthy controls.
The objective of the study is to determine whether 11C-metomidate PET can differentiate between BAH and APA./PAH
Study the mechanisms of BAT activity and the effects of BAT acitivity on energy homeostasis.
1 To evaluate the feasibility to measure cortisol levels in hair in healthy children and children with asthma who use inhaled corticosteroids2 To evaluate differences in cortisol levels in hair in healthy children and children with asthma who use…
The objective of the study is to determine whether it is necessary to take the blood pressure lowering medication (β-blocker, ACE-inhibitors or diuretics) of a patient into account prior to blood sampling for pheochromocytoma diagnostics. Therefore…
Our primary objectives are:- to estimate the prevalence of central adrenal insufficiency , defined as a plasma cortisol response <500 nmol/l in the low-dose ACTH test (see paragraph 8.3.5 of the protocol). - to describe immune dysfunction, i.…
We hypothesize that cardiovascular risk factors may already be present during childhood in CAH patients. Therefore, we will perform a cross-sectional study in CAH patients aged 1-16 years evaluating blood pressure, lipid profile, insulin sensitivity…
With a standardized approach in a population with difficult to treat hypertension we want to explore how frequenty PHA is a cause of hypertension and what the test characteristics of the aldosterone-renin ratio are. Additionally we want to…
Assess the prevalence of the metabolic syndrome and quality of life in patients with Addison*s disease treated with low dose GRT. Study the relation between GRT, QoL and glucocorticoid receptor polymorphisms